Armstrong AV Jr, Aedo A, Phelps S: Synovial sarcoma: a case report. .Clin Podiatr Med Surg 25::167. ,2008. .
Scully SP, Temple HT, Harrelson JM: Synovial sarcoma of the foot and ankle. .Clin Orthop Relat Res 364::220. ,1999. .
Andrassy R, Okcu M, Despa S, et al: Synovial sarcoma in children: surgical lessons from a single institution and review of the literature. .J Am Coll Surg 192::305. ,2001. .
Choong P, Prichard D, Sim F: Long-term survival in high grade soft tissue sarcoma: prognostic factors in synovial sarcoma. .Int J Oncol 7::161. ,1995. .
Brodsky J, Burt M, Hajdu S, et al: Tendosynovial sarcoma: clinicopathologic features, treatment, and prognosis. .Cancer 70::484. ,1992. .
Okcu M, Despa S, Choroszy M: Synovial sarcoma in children and adolescents: thirty three years of experience with multimodal therapy. .Med Pediatr Oncol 37::90. ,2001. .
Mazeron J, Suit H: Lymph nodes as sites of metastases from sarcomas of soft tissue. .Cancer 60::1800. ,1987. .
Williard W, Collin C, Casper E, et al: The changing role of amputation for soft tissue sarcoma of the extremity in adults. .Surg Gynecol Obstet 175::389. ,1992. .
Inagaki H, Nagasaka T, Otsuka T, et al: Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcoma. .Mod Pathol 13::482. ,2000. .
Winnepenninckx V, DeVos R, Debiec-Rychter M: Calcifying/ossifying synovial sarcoma shows t(X;18) with SSX2 involvement and mitochondrial calcifications. .Histopathology 38::141. ,2001. .
We report a case of a 40-year-old woman with synovial sarcoma who presented with neural symptoms in the medial aspect of the right foot and ankle. The radiographic appearance of the foot and ankle was unremarkable, but magnetic resonance imaging showed a relatively well-defined enhancing lesion in the plantar soft tissues extending from the master knot of Henry to the posterior tibialis tendon. After orthopedic oncologic evaluation and workup, the patient was ultimately treated with a transtibial amputation, and no evidence of recurrence or metastatic disease was seen at 6-month follow-up. (J Am Podiatr Med Assoc 100(3): 216–219, 2010)