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-
1
Atkins E: Fever: new perspectives on an old phenomenon. .N Engl J Med 308::958. ,1983. .
-
2
Romanovsky A: Thermoregulation: some concepts have changed: functional architecture of the thermoregulatory system. .Am J Physiol Regul Integr Comp Physiol 292::R37. ,2007. .
-
3
Cooper KE: Fever and Antipyresis, Cambridge University Press, Cambridge. ,1995. .
-
4
Sharma HS: Methods to produce hyperthermia-induced brain dysfunction. .Prog Brain Res 162::173. ,2007. .
-
5
Ivanov AI, Patel S, Kulchitsky VA, et al: Platelet-activating factor: a previously unrecognized mediator of fever. .J Physiol 553::221. ,2003. .
-
6
Dinarello C, Porat R: “Fever and Hypothermia,” in Harrison’s Principles of Internal Medicine, 17th Ed, ed by AS Fauci, p 117, McGraw Hill, New York. ,2008. .
-
7
Roth J, Rummel C, Barth SW, et al: Molecular aspects of fever. .Neurol Clin 24::421. ,2006. .
-
8
Blatteis CM, Sehic E: Fever: how may circulating pyrogens signal the brain?. News Physiol Sci 12::1. ,1997. .
-
9
Kozak W, Kluger MJ, Soszynski D, et al: “IL-6 and IL-1b in Fever: Studies Using Cytokine-Deficient (Knockout) Mice,” in Molecular Mechanisms in Fever, Vol 856, ed by MJ Kluger, p 33, New York Academy of Sciences, New York. ,1998. .
-
10
Ootsuka Y, Blessing WW, Steiner AA, et al: Fever response to intravenous prostaglandin E2 is mediated by the brain but does not require afferent vagal signaling. .Am J Physiol Regul Integr Comp Physiol 294::R1294. ,2008. .
-
11
Blatteis C: The onset of fever: new insights into its mechanism. .Prog Brain Res 162::3. ,2007. .
-
12
Milton AS, Wendlandt S: Effects on body temperature of prostaglandins of the A, E, and F series on injection into the third ventricle of unanaesthetized cats and rabbits. .J Physiol 218::325. ,1971. .
-
13
Ushikubi F, Segi E, Sugimoto Y, et al: Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3. .Nature 395::281. ,1998. .
-
14
Nakamura K, Matsumura K, Kaneko T, et al: The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area. .J Neurosci 22::4600. ,2002. .
-
15
Morrison SF, Nakamura K, Madden CJ: Central control of thermogenesis in mammals. .Exp Physiol 93::773. ,2008. .
-
16
Kluger MJ: Fever: role of pyrogens and cryogens. .Physiol Rev 71::93. ,1991. .
-
17
DuBois E: Why are fever temperatures over 106 degrees F rare?. Am J Med Sci 217::361. ,1949. .
-
18
Bouchama A, Knochel JP: Heat stroke. .N Engl J Med 346::1978. ,2002. .
-
19
Cooper K, Naylor AM, Veale WL: Evidence supporting a role for endogenous vasopressin in fever suppression in the rat. .J Physiol 387::163. ,1987. .
-
20
Sinha P, Schioth HB, Tatro JB: Activation of central melanocortin-4 receptor suppresses lipopolysaccha-ride-induced fever in rats. .Am J Physiol Regul Integr Comp Physiol 284::R1595. ,2003. .
-
21
Miyoshi M, Kitagawa Y, Imoto T, et al: Effect of natriuretic peptide receptor antagonist on lipopolysac-charide-induced fever in rats: is natriuretic peptide an endogenous antipyretic?. J Pharmacol Exp Ther 318::1163. ,2006. .
-
22
Morrow LE, McClellan JL, Conn CA, et al: Glucocorticoids alter fever and IL-6 responses to psychological stress and to LPS. .Am J Physiol 264::R1010. ,1993. .
-
23
Medzhitov R, Janeway C: Innate immunity. .N Engl J Med 343::338. ,2000. .
-
24
Sabroe I, Parker LC, Dower SK, et al: The role of TLR activation in inflammation. .J Pathol 214::126. ,2008. .
-
25
Dinarello CA: Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed. .J Endotoxin Res 10::201. ,2004. .
-
26
Dinarello CA, Wolff SM: “Exogenous Pyrogens,” in Pyretics and Antipyretics, ed by AS Milton, p 73, Springer-Verlag, Berlin. ,1982. .
-
27
Swartz MN, Simon HB: “Pathophysiology of Fever and Fever of Undetermined Origin,” in Scientific American Medicine, Vol 7, p 1, Freeman, San Francisco. ,1992. .
-
28
Arend WP, Dayer JM: Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. .Arthritis Rheum 33::305. ,1990. .
-
29
Elliott MJ, Maini RN, Feldmann M, et al: Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis. .Lancet 344::1105. ,1994. .
-
30
Moltz H: Fever: causes and consequences. .Neurosci Biobehav Rev 17::237. ,1993. .
-
31
Hasan MK, White AC: Psychogenic fever: entity or nonentity?. Postgrad Med 66::152. ,1979. .
-
32
Oka T, Oka K, Hori T: Mechanisms and mediators of psychological stress-induced rise in core temperature. .Psychosom Med 63::476. ,2001. .
-
33
Gordon C, Rowsey P: Poisons and fever. .Clin Exp Pharmacol Physiol 25::145. ,1998. .
-
34
Zell JA, Chang JC: Neoplastic fever: a neglected paraneoplastic syndrome. .Support Care Cancer 13::870. ,2005. .
-
35
Dinarello C, Bunn P: Fever. .Semin Oncol 24::288. ,1997. .
-
36
Chang JC: Neoplastic fever: a proposal for diagnosis. .Arch Intern Med 149::1728. ,1989. .
-
37
Petersdorf RG: Fever of unknown origin: an old friend revisited. .Ann Intern Med 152::21. ,1992. .
-
38
Cunha B: Fever of unknown origin: clinical overview of classic and current concepts. .Infect Dis Clin North Am 21::867. ,2007. .
-
39
Knockaert DC, Vanderschueren S, Blockmans D: Fever of unknown origin in adults: 40 years on. .J Intern Med 253::263. ,2003. .
-
40
Arnow PM, Flaherty JP: Fever of unknown origin. .Lancet 350::575. ,1997. .
-
41
Durack DT: “Fever of Unknown Origin,” in Fever: Basic Mechanisms and Management, 2nd Ed, ed by PA Mackowiak, p 237, Lippincott-Raven, Philadelphia. ,1997. .
-
42
Hanson MA: Drug fever: remember to consider it in diagnosis. .Postgrad Med 89::167. ,1991. .
-
43
Eyer F, Zilker T: Bench-to-bedside review: mechanisms and management of hyperthermia due to toxicity. .Crit Care 11::236. ,2007. .
-
44
Cunha BA: Drug fever: the importance of recognition. .Postgrad Med 80::123. ,1986. .
-
45
Nisijima K, Shioda K, Iwamura T: Neuroleptic malignant syndrome and serotonin syndrome. .Prog Brain Res 162::81. ,2007. .
-
46
Mueller P, Korey W: Death by “ecstasy”: the serotonin syndrome?. Ann Emerg Med 32::377. ,1998. .
-
47
Rosenberg H, Seitman D: “Pharmacogenetics,” in Clinical Anesthesia, ed by PG Barash, BF Cullen, RK Stoelting, p 459, JB Lippincott, Philadelphia. ,1989. .
-
48
Dykstra TJ, Menolasino MJ: Neuroleptic malignant syndrome: case report and review. .J Am Osteopath Assoc 97::355. ,1997. .
-
49
Musher DM, Fainstein V, Young EJ, et al: Fever patterns: their lack of clinical significance. .Arch Intern Med 139::1225. ,1979. .
-
50
Woodward TE: “The Fever Pattern as a Diagnostic Aid,” in Fever: Basic Mechanisms and Management, 2nd Ed, ed by PA Mackowiak, p 215, Lippincott-Raven, Philadelphia. ,1997. .
-
51
Sessler D: Temperature monitoring and perioperative thermoregulation. .Anesthesiology 109::318. ,2008. .
-
52
McCarthy PW, Heusch AI: The vagaries of ear temperature assessment. .J Med Eng Technol 30::242. ,2006. .
-
53
Mackowiak PA, Wasserman SS, Levin MM: A critical appraisal of 98.6°F, the upper limit of the normal body temperature, and other legacies of Carl Reinhold August Wunderlich. .JAMA 268::1578. ,1992. .
-
54
Henker R, Carlson KK: Fever: applying research to bedside practice. .AACN Adv Crit Care 18::76. ,2007. .
-
55
Cunha BA: The clinical significance of fever patterns. .Infect Dis Clin North Am 10::33. ,1996. .
-
56
Tunnessen WW: Signs and Symptoms in Pediatrics, Lippincott Williams & Wilkins, Philadelphia. ,1999. .
-
57
Schmitt B: Fever phobia: misconceptions of parents about fevers. .Am J Dis Child 134::176. ,1980. .
-
58
Crocetti M, Moghbeli N, Serwint J: Fever phobia revisited: have parental misconceptions about fever changed in 20 years?. Pediatrics 107::1241. ,2001. .
-
59
Haslam RH: “Febrile Seizures,” in Nelson Textbook of Pediatrics, 18th Ed, ed by RM Kliegman, RE Behrman, HB Jenson, et al, p 2457, Saunders, Philadelphia. ,2007. .
-
60
Knudsen FU: Febrile seizures: treatment and prognosis. .Epilepsia 41::2. ,2000. .
-
61
Baumann RJ: Technical report: treatment of the child with simple febrile seizures. .Pediatrics 103::e86. ,1999. .
-
62
Applegate MS, Lo W: Febrile seizures: current concepts concerning prognosis and clinical management. .J Fam Pract 29::422. ,1989. .
-
63
Kluger MJ: Fever revisited. .Pediatrics 90::846. ,1992. .
-
64
Uhari M, Rantala H, Vainionpaa L, et al: Effect of acetaminophen and of low intermittent doses of diazepam on prevention of recurrences of febrile seizures. .J Pediatr 126::991. ,1995. .
-
65
Fetveit A: Assessment of febrile seizures in children. .Eur J Pediatr 167::17. ,2008. .
-
66
Norman DC, Wong MB, Yoshikawa TT: Fever of unknown origin in older persons. .Infect Dis Clin North Am 21::937. ,2007. .
-
67
Jones SR: “Fever in the Elderly,” in Fever: Basic Mechanisms and Management, 1st Ed, ed by PA Mackowiak, p 233, Raven Press, New York. ,1991. .
-
68
Vane J: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. .Nat New Biol 231::232. ,1971. .
-
69
Schwartz JI, Chan CC, Mukhopadhyay S, et al: Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans. .Clin Pharmacol Ther 65::653. ,1999. .
-
70
Solomon DH, Schneeweiss S, Glynn RJ, et al: Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults. .Circulation 109::2068. ,2004. .
-
71
Hinz B, Cheremina O, Brune K: Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. .FASEB J 22::383. ,2007. .
-
72
Romanovsky AA, Almeida MC, Aronoff DM, et al: Fever and hypothermia in systemic inflammation: recent discoveries and revisions. .Front Biosci 10::2193. ,2005. .
-
73
Plaisance KI, Mackowiak PA: Antipyretic therapy: physiologic rationale, diagnostic implications, and clinical consequences. .Arch Med 160::449. ,2000. .
-
74
Isaacs SN, Axelrod PI, Lorber B: Antipyretic orders in a university hospital. .Am J Med 88::31. ,1990. .
-
75
Thomas V, Riegel B, Andrea J, et al: National survey of pediatric fever management practices among emergency department nurses. .J Emerg Nurs 20::505. ,1994. .
-
76
Styrt B, Sugarman B: Antipyresis and fever. .Arch Intern Med 150::1589. ,1990. .
-
77
Gozzoli V, Schottker P, Suter PM, et al: Is it worth treating fever in intensive care unit patients?. Arch Intern Med 161::121. ,2001. .
-
78
Mackowiak P: The febrile patient: diagnostic, prognostic and therapeutic considerations. .Front Biosci 9::2297. ,2004. .
-
79
Ferguson A: Evaluation and treatment of fever in intensive care unit patients. .Crit Care Nurs Q 30::347. ,2007. .
-
80
Axelrod YK, Diringer MN: Temperature management in acute neurologic disorders. .Neurol Clin 26::585. ,2008. .
-
81
Kluger MJ: “The Adaptive Value of Fever,” in Fever: Basic Mechanisms and Management, 1st Ed, ed by PA Mackowiak, p 105, Raven Press, New York. ,1991. .
-
82
Roberts NJ: Impact of temperature elevation on immunological defenses. .Rev Infect Dis 13::462. ,1991. .
-
83
Ostberg JR, Repasky EA: Emerging evidence indicates that physiologically relevant thermal stress regulates dendritic cell function. .Cancer Immunol Immunother 55::292. ,2006. .
-
84
Hasday JD, Garrison A: Antipyretic therapy in patients with sepsis. .Clin Infect Dis 31::S234. ,2000. .
-
85
Mackowiak PA, Plaisance KI: “Benefits and Risks of Antipyretic Therapy,” in Molecular Mechanisms of Fever, Vol 856, ed by MJ Kluger, p 214, New York Academy of Sciences, New York. ,1998. .
-
86
Walsh A, Edwards H: Management of childhood fever by parents: literature review. .J Adv Nurs 54::217. ,2006. .
-
87
Linder N, Sirota L, Snapir A, et al: Parental knowledge of the treatment of fever in children. .Israeli Med Assoc J 1::158. ,1999. .
-
88
Doran TF, De Angelis C, Baumgardner RA, et al: Acetaminophen: more harm than good for chickenpox?. J Pediatr 114::1045. ,1989. .
-
89
Kramer MS, Naimark LE, Roberts-Brauer R, et al: Risks and benefits of paracetamol antipyresis in young children with fever of presumed viral origin. .Lancet 337::591. ,1991. .
-
90
Casteels-Van Daele M: Management of childhood fever. .Lancet 338::1049. ,1991. .
-
91
Powell KR: “Fever,” in Nelson Textbook of Pediatrics, 18th Ed, ed by RM Kliegman, RE Behrman, HB Jenson, BM Stanton, p 1084, Saunders, Philadelphia. ,2007. .
-
92
Kurz A, Sessler DI, Lenhardt R: Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. .N Engl J Med 334::1209. ,1996. .
-
93
Frank SM, Kluger MJ, Kunkel SL: Elevated thermostatic setpoint in postoperative patients. .Anesthesiology 93::1426. ,2000. .
-
94
Engoren M: Lack of association between atelectasis and fever. .Chest 107::81. ,1995. .
-
95
Dayton MT: “Surgical Complications,” in Sabiston Textbook of Surgery, 17th Ed, ed by CM Townsend, p 297, Elsevier-Saunders, Philadelphia. ,2005. .
-
96
Ballestas HC: Postoperative fever: to what is the body really responding?. AORN J 86::983. ,2007. .
-
97
Fischer JE, Fegelman E, Johannigman J: “Surgical Complications,” in Principles of Surgery, 7th Ed, ed by S Schwarts, p 447, McGraw-Hill, New York. ,1999. .
-
98
Diamond PT, Macciochi SN: Predictive power of clinical symptoms in patients with presumptive deep venous thrombosis. .Am J Physical Med Rehabil 76::49. ,1997. .
-
99
Kang KH, Lee EY, Lee YJ, et al: Clinical features and risk factors of postsurgical gout. .Ann Rheum Dis 67::1271. ,2008. .
-
101
O’Grady NP, Barie PS, Bartlett JG, et al: Guidelines for evaluation of new fever in critically ill adult patients: 2008 update from the American College of Critical Care Medicine and the Infectious Diseases Society of America. .Crit Care Med 36::1330. ,2008. .
-
102
Kennedy C, Lefor AT: “Routine and Specialized Postoperative Care,” in Perioperataive Care, Anesthesia, Medicine and Surgery, ed by DJ Stone, p 758, Mosby, St Louis. ,1998. .
-
103
Lenhardt R, Negishi C, Sessler DI, et al: The effects of physical treatment on induced fever in humans. .Am J Med 106::550. ,1999. .
-
104
Larach MG: Making Anesthesia Safer: Unraveling the Malignant Hyperthermia Puzzle, Federation of American Societies of Experimental Biology, Bethesda, MD. ,2001. .
-
105
Denborough M: Malignant hyperthermia. .Lancet 352::1131. ,1998. .
-
106
Larach MG, Brandom BW, Allen GC, et al: Cardiac arrests and deaths associated with malignant hyperthermia in North America from 1987 to 2006: a report from the North American malignant hyperthermia registry of the malignant hyperthermia association of the United States. .Anesthesiology 108::603. ,2008. .
-
107
Rosero EB, Adesanya AO, Timaran CH, et al: Trends and outcomes of malignant hyperthermia in the United States, 2000 to 2005. .Anesthesiology 110::89. ,2009. .
-
108
MacLennan DH, Phillips MS: Malignant hyperthermia. .Science 256::789. ,1992. .
-
109
Loke J, MacLennan DH: Malignant hyperthermia and central core disease: disorders of Ca2+ release channels. .Am J Med 104::470. ,1998. .
-
110
Rosenberg H, Davis M, James D, et al: Malignant hyperthermia. .Orphanet J Rare Dis 2::21. ,2007. .
-
111
Donnelly AJ: Malignant hyperthermia. .AORN J 59::394. ,1994. .
-
112
Harrison GG: Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium. .Br J Anaesthesia 47::62. ,1975. .
-
113
Krause T, Gerbershagen MU, Fiege M, et al: Dantrolene: a review of its pharmacology, therapeutic use and new developments. .Anaesthesia 59::364. ,2004. .
-
114
Joseph WS: “Infections,” in Principles and Practice of Podiatric Medicine, ed by LA Levy, VJ Hetherington, p 277, Churchill-Livingstone, New York. ,1990. .
-
115
Duff GW, Atkins E, Malawista SE: The fever of gout: urate crystals activate endogenous pyrogen production from human and rabbit mononuclear phagocytes. .Trans Assoc Am Physicians 96::234. ,1983. .
-
116
Denno GJ, ed: Podiatric Therapeutic Digest, 3rd Ed, Odontos Publishing, Eastlake, OH. ,1999. .
-
117
Donoghue S: Fighting for every dollar. .Podiatry Manage 28::97. ,2009. .
-
118
Sulli MM, Etzel JV: Using of nonsteroidal anti-inflammatory drugs. .Podiatry Manage 21::109. ,2000. .
-
119
Miller SJ: Temperature regulation and postoperative fever: a preliminary study. .JAPA 74::373. ,1984. .
-
120
Strenge KB, Mangan DB, Idusuyi OB: Postoperative toxic shock syndrome after excision of a ganglion cyst from the ankle. .J Foot Ankle Surg 45::275. ,2006. .
-
121
Boegel WA, Miller SJ: “Perioperative Considerations for Foot and Ankle Surgery,” in Comprehensive Textbook of Foot Surgery, 2nd Ed, ed by ED McGlamry, AS Banks, MD Downey, p 181, Williams & Wilkins, Baltimore. ,1992. .
-
122
Gronen WW, Roda PL: Malignant hyperthermia: a case report. .JAPA 66::31. ,1976. .
-
123
Gohil B, Forman WM: Malignant hyperthermia: description and case report. .J Foot Surg 21::7. ,1982. .
-
124
Haber J, Hammer DJ, Butler B: Malignant hyperthermia: a review and case report. .JAPA 73::422. ,1983. .
-
125
Lowe MK: Malignant hyperthermia, a surgeon’s nightmare. .J Foot Surg 24::139. ,1985. .
-
126
Zanette G, Robb N, Zadra N, et al: Undetected central core disease myopathy in an infant presenting for clubfoot surgery. .Pediatr Anesth 17::380. ,2007. .
-
127
Shuaib A, Paasuke RT, Brownell KW: Central core disease: clinical features in 13 patients. .Medicine 66::389. ,1987. .
-
128
Bloch EC, Ginsberg B, Binner RA, et al: Limb tourniquets and central temperature in anesthetized children. .Pediatr Anesth 74::486. ,1992. .
-
129
Motegi Y, Shirai M, Arai M, et al: Malignant hyperthermia during epidural anesthesia. .J Clin Anesthesia 8::157. ,1996. .
-
Ibelgauf H: COPE: Cytokines & Cells Online Pathfinder Encyclopedia Web site. Available at: http://www.copewithcytokines.de/. Accessed May 28. ,2010. .
-
Malignant Hyperthermia Association of the United States Web site. Available at: http://www.mhaus.org. Accessed May 28. ,2010. .
-
NINDS febrile seizures information page. National Institute of Neurological Disorders and Stroke Web site. Available at: http://www.ninds.nih.gov/disorders/febrile_seizures/febrile_seizures.htm. Accessed May 28. ,2010. .
Fever—An Update
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Fever is an active yet nonspecific response of the body to infections and other insults that cause immune cells to release cytokines, resulting in a brain prostanoid–mediated rise in body temperature. The causes, types, clinical management, and postoperative consequences of fever are reviewed in this article. Physicians use fever as a clinical sign for diagnoses and prognoses, but “fevers of unknown origin” continue to be problematic. Fevers that arise 1 or 2 days after surgery are usually due to stress and trauma, but later postoperative fevers often have more serious causes and consequences, such as wound infection. Fever is commonly encountered by podiatric physicians and surgeons, and certain procedures with the lower extremity are more likely to eventuate in fever. (J Am Podiatr Med Assoc 100(4): 281–290, 2010)
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