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Wound Care

The Role of Advanced Wound-healing Technologies

Stephanie C. Wu Rosalind Franklin University of Medicine and Science, North Chicago, IL.

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William Marston Division of Vascular Surgery, Wound Healing/Limb Preservation Center, University of North Carolina School of Medicine, Chapel Hill, NC.

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David G. Armstrong Department of Surgery, Southern Arizona Limb Salvage Alliance, University of Arizona College of Medicine, Tucson, AZ.

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 DPM, MD, PhD

Wound repair and regeneration is a highly complex combination of matrix destruction and reorganization. Although major hurdles remain, advances during the past generation have improved the clinician’s armamentarium in the medical and surgical management of this problem. The purpose of this article is to review the current literature regarding the pragmatic use of three of the most commonly used advanced therapies: bioengineered tissue, negative-pressure wound therapy, and hyperbaric oxygen therapy, with a focus on the near-term future of wound healing, including stem cell therapy. (J Am Podiatr Med Assoc 100(5): 385–394, 2010)

Corresponding author: Stephanie C. Wu, DPM, MS, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Rd, North Chicago, IL 60064. (E-mail: stephanie. wu@rosalindfranklin.edu)