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Angiokeratoma Presenting as Plantar Verruca

A Case Study

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  • 1 California School of Podiatric Medicine at Samuel Merritt University, San Francisco, CA.
  • | 2 Department of Medicine, Office of Admission, California School of Podiatric Medicine at Samuel Merritt University, Oakland, CA.
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One of the more frequent pathologic conditions that podiatric physicians are confronted with is plantar verrucae. Plantar verrucae have been studied extensively in terms of morphological features and incidence in the population at large and in patients with human immunodeficiency virus infection. Solitary angiokeratomas can be morphologically similar to plantar verrucae, presenting as hyperkeratotic pedunculated lesions. We present a unique case study of a 40-year-old man with human immunodeficiency virus with a painful solitary angiokeratoma masquerading as plantar verrucae. The lesion demonstrated clinical signs consistent with those highlighted in the literature for verrucae, namely, showing as red and black lacunae, punctuated hyperkeratotic epidermis. We propose that solitary angiokeratomas should be an important part of a podiatric physician’s differential diagnosis in the lower extremity owing to the similarity of morphological features with plantar verrucae. (J Am Podiatr Med Assoc 100(6): 502–504, 2010)

Corresponding author: David Tran, DPM, Department of Medicine, California School of Podiatric Medicine at Samuel Merritt University, 3100 Telegraph Ave, #1000, Oakland, CA 94609. (E-mail: DTran@samuelmerritt.edu)