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Diffuse Large B-Cell Lymphoma of the Ankle

A Case Study of Surgical Intervention and Outcome

Mark J. Mendeszoon Private practice, Precision Orthopaedic Specialties, Chardon, OH; Ohio College of Podiatric Medicine and University Hospitals, Cleveland, OH.

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Kyle R. Wire Podiatry Primary Care and Surgery, Ohio College of Podiatric Medicine/University Hospitals Richmond Medical Center, Cleveland, OH.

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The most common type of non-Hodgkin’s lymphoma is the B-cell type. We report herein a type of B-cell lymphoma in an adult ankle. A 63-year-old woman presented with a painful growth on the anteromedial aspect of her right ankle that was later diagnosed as a form of non-Hodgkin’s lymphoma. Clinically, the single mass appeared bluish in color, painful on palpation, and warm to the touch. The overlying skin was friable, and the lesion did not transilluminate. Histopathologic examination revealed a diffuse large B-cell lymphoma of germinal center origin on surgical excision. This case report focuses on the clinical presentation, surgical intervention, and overall outcome of a rare case of lymphoma of the ankle. (J Am Podiatr Med Assoc 100(6): 505–510, 2010)

Corresponding author: Mark J. Mendeszoon, DPM, Precision Orthopaedic Specialties, 150 Seventh Ave, Ste 200, Chardon, OH 44024. (E-mail: dr1zoom@roadrunner.com)
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