Cover Journal of the American Podiatric Medical Association
Journal of the American Podiatric Medical Association
ISSN:
8750-7315
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Article Type:
Original Articles
Online Publication Date:
Mar 2011

The Use of Superoxidized Aqueous Solution versus Saline as a Replacement Solution in the Versajet Lavage System in Chronic Diabetic Foot Ulcers

A Pilot Study

Frank L. Bowling University Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, England.

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 PhD
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Ryan T. Crews Scholl College’s Center for Lower Extremity Ambulatory Research, Rosalind Franklin University, North Chicago, IL.

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 MS
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Eleanna Salgami University Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, England.

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 MD, PhD
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David G. Armstrong Southern Arizona Limb Salvage Alliance, University of Arizona, Tucson, AZ.

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 DPM, MD, PhD
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Andrew J.M. Boulton University Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, England.
Division of Endocrinology, Metabolism, and Diabetes, University of Miami School of Medicine, Miami, FL.

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DOI:
https://doi.org/10.7547/1010124
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Background: The removal of necrotic tissue from chronic wounds is required for wound healing to occur. Hydrodebridement (jet lavage) and superoxidized aqueous solution have been independently used for debriding wounds. We sought to investigate the use of superoxidized aqueous solution with a jet lavage system.

Methods: Twenty patients with diabetic foot ulcers were randomly assigned in a 1:1 ratio to receive jet lavage debridement with either superoxidized aqueous solution or standard saline weekly.

Results: There was no significant difference between the two treatments in the reduction of bacterial load or wound size in 4 weeks. No adverse reactions were reported for either treatment.

Conclusions: The use of superoxidized aqueous solution for jet lavage debridement seemed to be as safe and effective as saline. Future investigations should concentrate on whether superoxidized aqueous solution may reduce the bacterial air contamination associated with hydrodebridement. (J Am Podiatr Med Assoc 101(2): 124–126, 2011)

Corresponding author: Ryan T. Crews, MS, Scholl College’s Center for Lower Extremity Ambulatory Research, Rosalind Franklin University, 3333 Green Bay Rd, North Chicago, IL 60064. (E-mail: ryan.crews@rosalindfranklin.edu)
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