• 1

    Armstrong DG, Lipsky BA: Diabetic foot infections: stepwise medical and surgical management.Int Wound J 1::123. ,2004. .

  • 2

    Dalla Paola L, Brocco E, Senesi A, et al: Use of Dermacyn, a new antiseptic agent for the local treatment of diabetic foot ulcers.J Wound Healing 2::201. ,2005. .

    • Search Google Scholar
    • Export Citation
  • 3

    Armstrong DG, Lavery L: Diabetic foot ulcers: prevention, diagnosis and classification.Am Fam Physician 57::1325. ,1998. .

  • 4

    Sainsbury DC: Evaluation of the quality and cost-effectiveness of Versajet hydrosurgery.Int Wound J 6::24. ,2009. .

  • 5

    Bowling FL, Stickings DS, Edwards-Jones V, et al: Hydrodebridement of wounds: effectiveness in reducing wound bacterial contamination and potential for air bacterial contamination.J Foot Ankle Res 2::13. ,2009. .

    • PubMed
    • Search Google Scholar
    • Export Citation

The Use of Superoxidized Aqueous Solution versus Saline as a Replacement Solution in the Versajet Lavage System in Chronic Diabetic Foot Ulcers

A Pilot Study

Frank L. Bowling University Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, England.

Search for other papers by Frank L. Bowling in
Current site
Google Scholar
PubMed
Close
 PhD
,
Ryan T. Crews Scholl College’s Center for Lower Extremity Ambulatory Research, Rosalind Franklin University, North Chicago, IL.

Search for other papers by Ryan T. Crews in
Current site
Google Scholar
PubMed
Close
 MS
,
Eleanna Salgami University Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, England.

Search for other papers by Eleanna Salgami in
Current site
Google Scholar
PubMed
Close
 MD, PhD
,
David G. Armstrong Southern Arizona Limb Salvage Alliance, University of Arizona, Tucson, AZ.

Search for other papers by David G. Armstrong in
Current site
Google Scholar
PubMed
Close
 DPM, MD, PhD
, and
Andrew J.M. Boulton University Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, England.
Division of Endocrinology, Metabolism, and Diabetes, University of Miami School of Medicine, Miami, FL.

Search for other papers by Andrew J.M. Boulton in
Current site
Google Scholar
PubMed
Close
 MD
Restricted access

Background: The removal of necrotic tissue from chronic wounds is required for wound healing to occur. Hydrodebridement (jet lavage) and superoxidized aqueous solution have been independently used for debriding wounds. We sought to investigate the use of superoxidized aqueous solution with a jet lavage system.

Methods: Twenty patients with diabetic foot ulcers were randomly assigned in a 1:1 ratio to receive jet lavage debridement with either superoxidized aqueous solution or standard saline weekly.

Results: There was no significant difference between the two treatments in the reduction of bacterial load or wound size in 4 weeks. No adverse reactions were reported for either treatment.

Conclusions: The use of superoxidized aqueous solution for jet lavage debridement seemed to be as safe and effective as saline. Future investigations should concentrate on whether superoxidized aqueous solution may reduce the bacterial air contamination associated with hydrodebridement. (J Am Podiatr Med Assoc 101(2): 124–126, 2011)

Corresponding author: Ryan T. Crews, MS, Scholl College’s Center for Lower Extremity Ambulatory Research, Rosalind Franklin University, 3333 Green Bay Rd, North Chicago, IL 60064. (E-mail: ryan.crews@rosalindfranklin.edu)