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Charcot-Marie-Tooth Disease Complicating Type 2 Diabetes

Htet Htet Ne Win Department of Academic Endocrinology, Beaumont Hospital, Dublin, Ireland.

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Colin Davenport Department of Academic Endocrinology, Beaumont Hospital, Dublin, Ireland.

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Siobhan Delaney Department of Academic Endocrinology, Beaumont Hospital, Dublin, Ireland.

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Margaret Kelly Department of Academic Endocrinology, Beaumont Hospital, Dublin, Ireland.

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Diarmuid Smith Department of Academic Endocrinology, Beaumont Hospital, Dublin, Ireland.

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Although both conditions are relatively common, there are very few descriptions of type 2 diabetes mellitus coexisting with Charcot-Marie-Tooth disease (CMT). This case report and literature review describes a 53-year-old Irish man who presented with type 2 diabetes and significant neuropathy, and who was subsequently diagnosed with CMT type 1A. This case report will also discuss how to differentiate diabetic neuropathy from a progressive hereditary neuropathy and how coexistence aggravates the progression of neuropathy thus necessitating early diagnosis. (J Am Podiatr Med Assoc 101(4): 349–352, 2011)

Corresponding author: Htet Htet Ne Win, Department of Academic Endocrinology, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland. (E-mail: hnewin@gmail.com)