• 1

    Chen, QR, G Vansant, K Oades, et al. :Diagnosis of the small round blue cell tumors using multiplex polymerase chain reaction. .J Molec Diag 9::80. ,2007. .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2

    Whang-Peng, J, TJ Triche, T Knutsen, et al. :Cytogenetic characterization of selected small round cell tumors of childhood. .Cancer Genet Cytogenet 21::185––208. ,1986. .

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 3

    Weiss, SW and JR Goldblum. : “Immunohistochemistry for Analysis of Soft Tissue Tumors. ,” inEnzinger and Weiss’s Soft Tissue Tumors, ,5th ed. . ed bySchmitt, W. , p129. ,Mosby. ,Philadelphia. ,2008. .

    • Search Google Scholar
    • Export Citation
  • 4

    Davicioni, E, MJ Anderson, FG Finckenstein, et al. :Molecular classification of rhabdomyosarcoma – genotypic and phenotypic determinants of diagnosis. .Am J Pathol 174::550––564. ,2009. .

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 5

    Skubitz, KM and DR D’Adamo. :Sarcoma. .Mayo Clin Proc 82::1409. ,2007. .

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 6

    Bernstein, M, H Kovar, M Paulussen, et al. :Ewing’s Sarcoma family of tumors: current management. .Oncologist 5::503. ,2006. .

  • 7

    Jelinek, JS, MJ Kransdorf, BM Shmookler, et al. :Liposarcoma of the extremities: MR and CT findings in the histologic subtypes. .Radiology 186::455. ,1993. .

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8

    Kilpatrick, SE, J Doyon, PF Choong, et al. :The clinicopathologic spectrum of myxoid and round cell liposarcoma: a study of 95 cases. .Cancer 77::1450. ,1996. .

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9

    Delattree, O, J Zucman, T Melot, et al. :The Ewing family of tumors – a subgroup of small round cell tumors defined by specific chimeric transcripts. .N Engl J Med 331::294. ,1994. .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10

    Zagar, TM, TJ Triche, and TJ Kinsella. :Extraossous Ewing’s sarcoma: 25 years later. .J Clin Oncol 26::4230. ,2008. .

  • 11

    Alava, E and W Gerald. :Molecular biology of the Ewing’s sarcoma/primitive neuroectodermal tumor family. .J Clin Oncol 18::204. ,2000. .

  • 12

    Davis, RI and SA Henderson. :Synovial sarcoma: an underdiagnosed swelling of the foot. .The Foot 1::185. ,1992. .

  • 13

    Vargas, B and M Clayer. :Synovial cell sarcoma .Available http://www.emedicine.com/orthoped/topic564.htm. .Accessed May 31, 2011.

  • 14

    Eilber, FC and SM Dry. :Diagnosis and management of synovial sarcoma. .J Surg Oncol 97::314. ,2008. .

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 15

    Jackson, TO, T DeLauro, and J Prignano. :Synovial sarcoma: an unusual case presentation. .JAPMA 88::149. ,1998. .

  • 16

    Siegel, HJ, W Sessions, MA Casillas, et al. :Synovial sarcoma: clinicopathologic features, treatment, and prognosis. .Orthopedics 30::1020. ,2007. .

  • 17

    Degroot III, H . :Approach to the management of soft tissue tumors of the foot and ankle. .Foot Ankle Spec 1::168. ,2008. .

  • 18

    Scully, SP, HT Temple, and JM Harrelson. :Synovial sarcoma of the foot and ankle. .Clin Orthop Relat Res 364::220. ,1999. .

  • 19

    Clark, MA, C Fischer, I Judson, et al. :Soft-tissue sarcomas in adults. .N Engl J Med 353::701. ,2005. .

  • 20

    Papagelopoulos, PJ, AF Mavrogenis, A Badekas, et al. :Foot malignancies: a multidisciplinary approach. .Foot Ankle Clin 8::751. ,2003. .

  • 21

    Masui, F, Y Matsuno, R Yokoyama, et al. :Synovial sarcoma, histologically mimicking primitive neuroectodermal tumor/Ewing’s sarcoma at distant sites. .Jpn J Clin Oncol 29::438. ,2000. .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 22

    Bakotic, BW and P Borkorski. :Primary soft-tissue neoplasms of the foot: the clinicopathologic features of 401 cases. .J Foot Ankle Surg 40::28. ,2001. .

  • 23

    Lewis, JJ, CR Antonescu, DHY Leung, et al. :Synovial sarcoma: a multivariate analysis of prognostic factors in 112 patients with primary localized tumors of the extremity. .J Clin Oncol 18::2087. ,2000. .

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 24

    Eilber, FC, MF Brennan, FR Eilber, et al. :Chemotherapy is associated with improved survival in adult patients with primary extremity synovial sarcoma. .Ann Surg 246::105. ,2007. .

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation

Small Blue Round Cell Tumor

An Unusual Case Presentation in the Foot

J. Marshall Devall Department of Surgery, Division of Podiatry, Scott & White Healthcare, Texas A&M Health Science Center College of Medicine, Temple, TX.

Search for other papers by J. Marshall Devall in
Current site
Google Scholar
PubMed
Close
 DPM
,
Katherine M. Frush Des Moines University College of Podiatric Medicine and Surgery, Des Moines, IA.

Search for other papers by Katherine M. Frush in
Current site
Google Scholar
PubMed
Close
 DPM
, and
Lori Steiner Des Moines University College of Podiatric Medicine and Surgery, Des Moines, IA.

Search for other papers by Lori Steiner in
Current site
Google Scholar
PubMed
Close
 BS
Restricted access

Small blue round cell tumors of childhood rarely present in the foot or ankle. The following is a case presentation of an 18-year-old male with a large soft-tissue mass of the foot with associated lung metastasis. A definitive diagnosis could not be fully made, even with immunohistochemical and genetic testing. Diagnosis favored poorly differentiated synovial sarcoma. (J Am Podiatr Med Assoc 101(4): 363–369, 2011)

Corresponding author: Katherine M. Frush, DPM, Des Moines University College of Podiatric Medicine and Surgery, 3200 Grand Avenue, Des Moines, Iowa 50310. (E-mail: katherine.frush@dmu.edu)