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The Charcot Foot in Diabetes

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  • 1 Amputation Prevention Center at Valley Presbyterian Hospital, Los Angeles, CA.
  • | 2 Carl T. Hayden Veterans Affairs Medical Center, Phoenix, AZ.
  • | 3 Southern Arizona Limb Salvage Alliance (SALSA), University of Arizona College of Medicine, Tucson, AZ.
  • | 4 Department of Medicine, University of Manchester, Manchester, UK.
  • | 5 Diabetic Foot Clinic, King’s College Hospital, London, UK.
  • | 6 Diabetes and Metabolic Diseases Department, Pitié-Salpêtrière University Hospital, Paris, France.
  • | 7 Department of Diabetes and Endocrinology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
  • | 8 Institute for Clinical and Experimental Medicine, Diabetes Centre, Prague, Czech Republic.
  • | 9 Department of Diabetes and Angiology, Marienkrankenhaus, Soest, Germany.
  • | 10 Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA.
  • | 11 Department of Orthopedic Surgery, Loyola University Health System, Maywood, IL.
  • | 12 Diabetes Center and Foot Care Unit A, Gemelli Hospital, Catholic University, Rome, Italy.
  • | 13 Podiatry Service, Veterans Affairs Medical Center, Lebanon, PA.
  • | 14 Department of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.
  • | 15 Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.
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The diabetic Charcot foot syndrome is a serious and potentially limb-threatening lower-extremity complication of diabetes. First described in 1883, this enigmatic condition continues to challenge even the most experienced practitioners. Now considered an inflammatory syndrome, the diabetic Charcot foot is characterized by varying degrees of bone and joint disorganization secondary to underlying neuropathy, trauma, and perturbations of bone metabolism. An international task force of experts was convened by the American Diabetes Association and the American Podiatric Medical Association in January 2011 to summarize available evidence on the pathophysiology, natural history, presentations, and treatment recommendations for this entity. (J Am Podiatr Med Assoc 101(5): 437–446, 2011)

Corresponding author: Lee C. Rogers, DPM, Valley Presbyterian Hospital, Amputation Prevention Center, 15107 Vanowen St, Los Angeles, CA 91405. (E-mail: lee.c.rogers@gmail.com)