Van Den Bekerom, MP, M Hogervorst, and HW Bolhuis. :Operative aspects of the syndesmotic screw: review of current concepts. .Injury 39::491. ,2008. .
Boden, SD, PA Labropaulos, and P McCowin. :Mechanical considerations for the syndesmosis screw. .J Bone Joint Surg Am 71::15. ,1989. .
Close, JR . :Some applications of the functional anatomy of the ankle joint. .J Bone Joint Surg Am 38::761. ,1956. .
Rasmussen, O, I Tovborg Jensen, and S Boe. :Distal tibiofibular ligaments: analysis of function. .Acta Orthop Scand 53::681. ,1982. .
Hansen, M, L Le, and S Wertheimer. :Syndesmosis fixation: analysis of shear stress via axial load on 3.5-mm and 4.5-mm quadricortical syndesmotic screws. .J Foot Ankle Surg 45::65. ,2006. .
Lauge Hansen, N . :Fractures of the ankle: II. Combined radiographic and experimental-roentgenologic investigations. .Arch Surg 60::957. ,1985. .
Mosier LaClair, S, H Pike, and G Pomeroy. :Syndesmosis injuries: acute, chronic, new techniques for failed management. .Foot Ankle Clin 7::551. ,2002. .
Beumer, A, MM Campo, and R Niesing. :Screw fixation of the syndesmosis: a cadaver model comparing stainless steel and titanium screws and three and four cortical fixation. .Injury 36::60. ,2005. .
Hahn, DM and CL Colton. : “Malleolar Fractures. ,” inAO Principles of Fracture Management. , edited byRüedi, TP and WL Murphy. , p559. ,Thieme. ,New York. ,2000. .
Hoiness, P and K Stromsoe. :Tricortical versus quadricortical syndesmosis fixation in ankle fractures: a prospective, randomized study comparing two methods of syndesmosis fixation. .J Orthop Trauma 18::331. ,2004. .
Thompson, MC and DS Gesink. :Biomechanical comparison of syndesmosis fixation with 3.5- and 4.5-millimeter stainless steel screws. .Foot Ankle Int 21::736. ,2000. .
Moore Jr, JA, JR Shank, SJ Morgan, et al. :Syndesmosis fixation: a comparison of three and four cortices of screw fixation without hardware removal. .Foot Ankle Int 27::567. ,2006. .
Walke, W, Z Paszenda, and M Kaczmarek. :Biomechanical analysis of tibia: double threaded screw fixation. .Arch Materials Sci Eng 30::41. ,2008. .
Erkmen, E, B Şimşek, E Yücel, et al. :Three-dimensional finite element analysis used to compare methods of fixation after sagittal split ramus osteotomy: setback surgery-posterior loading. .Br J Oral Maxillofac Surg 43::97. ,2005. .
Gray, HA, F Taddei, AB Zavatsky, et al. :Experimental validation of a finite element model of a human cadaveric tibia. .J Biomech Eng 130::31. ,2008. .
Haraguchi, N, RS Armiger, MS Myerson, et al. :Prediction of three-dimensional contact stress and ligament tension in the ankle during stance determined from computational modeling. .Foot Ankle Int 30::177. ,2009. .
Attarian, DE, HJ McCrackin, DP Devito, et al. :Biomechanical characteristics of human ankle ligaments. .Foot Ankle 6::54. ,1985. .
Beumer, A, WL van Hemert, BA Swierstra, et al. :A biomechanical evaluation of the tibiofibular and tibiotalar ligaments of the ankle. .Foot Ankle Int 24::426. ,2003. .
Stauffer, RN, EY Chao, and RC Brewster. :Force and motion analysis of the normal, diseased, and prosthetic ankle joint. .Clin Orthop Relat Res 127::189. ,1977. .
Nousiainen, MT, AJ McConnell, R Zdero, et al. :The influence of the number of cortices of screw purchase and ankle position in Weber C ankle fracture fixation. .J Orthop Trauma 22::473. ,2008. .
Manjoo, A, DW Sanders, C Tieszer, et al. :Functional and radiographic results of patients with syndesmotic screw fixation: implications for screw removal. .J Orthop Trauma 24::2. ,2010. .
Hamid, N, BJ Loeffler, W Braddy, et al. :Outcome after fixation of ankle fractures with an injury to the syndesmosis: the effect of the syndesmosis screw. .J Bone Joint Surg Br 91::1069. ,2009. .
Heim, D, U Heim, and P Regazzoni. :Malleolar fractures with ankle joint instability: experience with the positioning screw. .Unfallchirurgie 19::307. ,1993. .
De Souza, L, R Gustilo, and T Meyer. :Results of operative treatment of displaced external rotation-abduction fractures of the ankle. .J Bone Joint Surg Am 67::1066. ,1985. .
Xenos, J, W Hopkinson, M Mulligan, et al. :The tibiofibular syndesmosis: evaluation of the ligamentous structures, methods of fixation, and radiographic assessment. .J Bone Joint Surg Am 77::847. ,1995. .
Muller, ME, M Allgower, R Schneider, et al. :Manual of Internal Fixation: Techniques Recommended by the AO-ASIF Group. , p610. ,Springer Verlag. ,Sehir, Turkey. ,1991. .
Henley, M, M Law, and S Henry. :Removal of broken syndesmotic screws: a technical tip. .Orthopedics 12::643. ,1994. .
Wuest, T . :Injuries to the distal lower extremity syndesmosis. .J Am Acad Orthop Surg 5::172. ,1997. .
Vander Griend, R, JD Michelson, and LB Bone. :Fractures of the ankle and the distal part of the tibia. .Instr Course Lect 46::311. ,1997. .
Heim, U and KM Pfeiffer. :Small Fragment Set Manual: Technique Recommended by the ASIF Group, ,2nd Ed. , p141. ,Springer Verlag. ,New York. ,1981. .
McBryde, A, B Chiasson, and A Wilhelm. :Syndesmotic screw placement: a biomechanical analysis. .Foot Ankle Int 18::262. ,1997. .
Seitz Jr, WH, EJ Bachner, and LJ Abram. :Repair of the tibiofibular syndesmosis with a flexible implant. .J Orthop Trauma 5::78. ,1991. .
Stiehl, JB, RR Needleman, and DA Skrade. :The biomechanical effect of the syndesmotic screw on ankle motion. .AO/ ASIF Dialogue 2::1. ,1989. .
Mast, JW and WA Teipner. :A reproducible approach to internal fixation of adult ankle fractures: rationale, technique, and early results. .Orthop Clin North Am 11::661. ,1980. .
Michelson, JD . :Fractures about the ankle. .J Bone Joint Surg Am 77::142. ,1995. .
Michelson, JD and B Waldman. :An axially loaded model of the ankle after pronation external rotation injury. .Clin Orthop 328::285. ,1996. .
Parfenchuck, TA, JM Frix, and SL Bertrand. :Clinical use of a syndesmotic screw in stage IV pronation-external rotation ankle fractures. .Orthop Rev Suppl 23.:1994. .
Pereira, DS, KJ Koval, and RB Resnick. :Tibiotalar contact area and pressure distribution: the effect of mortise widening and syndesmosis fixation. .Foot Ankle Int 17::269. ,1996. .
Solari, J, J Benjamin, and J Wilson. :Ankle mortise stability in Weber C fractures: indications for syndesmotic fixation. .J Orthop Trauma 5::190. ,1991. .
Thodarson, DB, TP Hedman, and D Gross. :Biomechanical evaluation of polylactide absorbable screws used for syndesmosis injury repair. .Foot Ankle Int 18::622. ,1997. .
Wieding, J, R Souffrant, A Fritsche, et al. :Finite element analysis of osteosynthesis screw fixation in the bone stock: an appropriate method for automatic screw modelling. .PLoS One 7::e33776. ,2012. .
Use of thicker and longer (four cortices) screws or of multiple screws seems to be more stable and efficient for syndesmosis fixation.
A three-dimensional finite element model of an ankle was constructed from serial axial sections from an existing two-dimensional computed tomographic image. Constructions of syndesmosis fixation with 3.5-mm single tricortical, 3.5-mm single quadricortical, 3.5-mm double tricortical, 3.5-mm double quadricortical, 4.5-mm single tricortical, and 4.5-mm single quadricortical screws were performed on this model. Physiologic loads approximating those during stance phase normal walking were applied to this ankle system. Stress values on the screws using the six fixation methods were compared.
The highest maximum stress was determined over 3.5-mm cortical screws applied as single quadricortical, and the lowest maximum stress was determined over the 4.5-mm cortical screw applied as single quadricortical. Stress on the 3.5-mm single screw with quadricortical application was found to be higher than that with tricortical application and also compared with the 4.5-mm quadricortical screw application. Differences between the 4.5-mm single tricortical and quadricortical screws and between the 3.5-mm single tricortical and 3.5-mm double tricortical screw applications were not significant.
Quadricortical application of 3.5-mm single screws and tricortical application of 3.5-mm double cortical screws are not good choices for syndesmosis fixation. If the plan is tricortical application, a 3.5-mm single cortical screw is adequate. If quadricortical application of syndesmosis fixation is planned, a 4.5-mm cortical screw should be used. (J Am Podiatr Med Assoc 103(3): 174–180, 2013)