advertising
-
1
Duprat JP, Landman G, Salvajoli JV, et al: A review of the epidemiology and treatment of Merkel cell carcinoma. Clinics 66: 1817, 2001.
-
2
Koljonen V: Merkel cell carcinoma. World J Surg Oncol 4: 7, 2006.
-
3
Rockville Merkel Cell Carcinoma Group: Merkel cell carcinoma: recent progress and current priorities on etiology, pathogenesis, and clinical management. J Clin Oncol 27: 4021, 2009.
-
4
Papamichail M, Nikolaidis I, Nikolaidis N, et al: Merkel cell carcinoma of the upper extremity: case report and an update. World J Surg Oncol 6: 32, 2008.
-
5
Cheung M, Lee H, Purkayastha S, et al: Ileocaecal recurrence of Merkel cell carcinoma of the skin: a case report. J Med Case Reports 4: 43, 2010.
-
6
Heath M, Jaimes N, Lemos B, et al: Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. J Am Acad Dermatol 58: 375, 2008
-
7
Lemos BD, Storer BE, Iyer JG, et al: Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system for this cancer. J Am Acad Dermatol. 63: 751, 2010.
Merkel Cell Carcinoma of the Lower Extremity
A Case Report
Search for other papers by Dominic J. Roda in
Current site
Google Scholar
PubMed
Search for other papers by Brian Albano in
Current site
Google Scholar
PubMed
Search for other papers by Bharti Rathore in
Current site
Google Scholar
PubMed
Search for other papers by Linda Zhou in
Current site
Google Scholar
PubMed
Merkel cell carcinoma is a rare, often fatal, neuroendocrine cutaneous malignancy with a highly variable clinical presentation. Due to the rapid progression of the disease, early detection and treatment is vital to survival. Here, we report the case of a 45-year-old woman whose podiatrist noticed an unusual lesion on her lower left leg and referred her to a dermatologist for work-up. A diagnostic excisional biopsy confirmed the diagnosis and was followed by treatment that included wide local excision of the primary lesion with subsequent chemotherapy and radiation. At the time of diagnosis, sentinel lymph node biopsy was positive. Due to the increasing prevalence of Merkel cell carcinoma in the past decade and its propensity to present on the lower extremity, podiatric physicians need to be aware of the clinical presentation and treatment guidelines for this elusive disease.
advertising
