• 1

    Touart DM, Sau P: Cutaneous deposition diseases. Part I. JAAD 392: 149, 1998.

  • 2

    James WD, Berger T, Elston D: Errors in Metabolism,” in Andrews' Diseases of the Skin, edited by R Gabbedy, p 506, Saunders, Philadelphia, 2011.

  • 3

    Schwendiman MN, Beachkofsky TM, Wisco OJ, et al: Primary cutaneous nodular amyloidosis: case report and review of the literature. Cutis 84: 87, 2009.

  • 4

    Borowicz J, Gillespie M, Miller R: Cutaneous amyloidosis. Skin 9: 96, 2011.

  • 5

    Wollons A, Black MM: Nodular localized primary cutaneous amyloidosis: a long-term follow up study. Br J Dermatol 145: 105, 2001.

  • 6

    Kalajian AH, Waldman M, Knable A: Nodular primary localized cutaneous amyloidosis after trauma: a case report and discussion of the rate of progression to systemic amyloidosis. JAAD 57: S26, 2007.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7

    Borrowman TA, Lutz ME, Walsh JS: Cutaneous nodular amyloidosis masquerading as a foot callus. JAAD 49: 307, 2003.

  • 8

    Moon A, Calamia K, Walsh J: Nodular amyloidosis review and long-term follow up of 16 cases. Arch Dermatol 139: 1157, 2003.

  • 9

    Clos AL, Lasagna-Reeves CA, Castillo-Carranza DL, et al: Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis. BJD 165: 134954, 2011.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10

    Meijer JM, Schonland SO, Palladini G, et al: Sjögren's syndrome and localized nodular cutaneous amyloidosis: coincidence or a distinct clinical entity? Arthritis Rheum 58: 1992, 2008.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11

    Yoneyama K, Tochigi N, Oikawa A, et al: Primary localized cutaneous nodular amyloidosis in a patient with Sjögren's syndrome: a review of the literature. J Dermatol 32: 120, 2005.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12

    Praprotnik S, Tomsic M, Perkovic T, et al: Is Sjögren's syndrome involved in the formation of localized nodular amyloidosis? Clin Exp Rheumatol 19: 735, 2001.

  • 13

    Music E, Piette W: Cutaneous amyloidosis: similar, but different. Am J Med 123: 423, 2010.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 14

    Seebacher C, Bouchara JP: Updates on the epidemiology of dermatophyte infections. Mycopathologia 166: 335, 2008.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation

Nodular Amyloidosis

Clinical Recognition of an Unusual Entity

Landon E. Stigall Geisinger Health System, Danville, PA.

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Michelle Maroon Geisinger Health System, Danville, PA.

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David L. Troutman Geisinger Health System, Danville, PA.

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Nodular amyloidosis is a protein deposition disorder that is important to recognize in the clinical setting. Identification and differentiation from primary systemic amyloidosis, which has an identical cutaneous presentation, but serious systemic implications, is of particular significance. Our case report highlights two patients who presented with isolated involvement of the plantar surface and ungual phalanges, each with concomitant tinea pedis. Recognition and diagnosis of cutaneous amyloidosis enables discrimination from systemic disease, and if found, prompt institution of appropriate treatment.

Corresponding author: Landon E. Stigall, MD, Geisinger Health System, 115 Woodbine Lane, Danville, PA 17821. (E-mail: lstigall@gmail.com)
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