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Solitary Eccrine Syringofibroadenoma and Successful Treatment with Cryotherapy

Dilek Biyik Ozkaya Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey.

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Ozlem Su Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey.

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Anıl Gülsel Bahalı Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey.

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Bugce Topukçu Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey.

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Didem Dizman Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey.

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Zeynep Tosuner Department of Pathology, Bezmialem Vakif University, Istanbul, Turkey.

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Cuyan Demirkesen Department of Pathology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.

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Nahide Onsun Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey.

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First described in 1963, eccrine syringofibroadenoma (ESFA) is a rare benign tumor that proliferates with differentiation toward ductal eccrine structures. There are many clinical presentations, including plaques, papules, verrucous plaques, keratotic tumors, and solitary tumors. The age of onset varies, with presentation between 16 and 80 years; however, solitary lesions are seen most commonly in the seventh and eighth decades. Here, we present the case of a 72-year-old woman referred to our outpatient clinic with a nodule on her leg. The histopathology result was ESFA. The lesion regressed after six cryotherapy sessions. Physicians should consider the possibility of ESFA and must remember its malignant potential in elderly patients.

Corresponding author: Dilek Biyik Ozkaya, Bezmialem Vakif University, Medical Faculty, Dermatoveneorology Department, Adnan Menderes Bulvarı (Vatan Cad.) P.K.: 34093 Fatih/Istanbul, Turkey. (E-mail: dilekozkaya@gmail.com)
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