Mahlen SD : Serratia infections: from military experiments to current practice. Clin Microbiol Rev 24: 755, 2011.
Gaughran ER: From superstition to science: the history of a bacterium. Trans N Y Acad Sci 31: 3, 1969.
Breed RS, Breed ME: The type species of the genus Serratia, commonly known as Bacillus prodigiosus. J Bacteriol 9: 545, 1924.
Yu VL : Serratia marcescens: historical perspective and clinical review. N Engl J Med 300: 887, 1979.
Merlino CP: Bartolomeo Bizio's letter to the most eminent priest, Angelo Bellani, concerning the phenomenon of the red colored polenta. J Bacteriol 9: 527, 1924.
Chi SY, Kim TO, Park CW, et al: Bacterial pathogens of ventilator associated pneumonia in a tertiary referral hospital. Tuberc Respir Dis (Seoul) 73: 32, 2012.
Tan N, Galvante PRE, Chee SP: Endogenous Serratia marcescens endophthalmitis: an atypical presentation. Eye (Lond) 28: 108, 2014.
Crowder JG, Gikley GA, White AC: Serratia marcescens bacteremia. Arch Intern Med 128: 247, 1971.
Cope TE, Cope W, Beaumont DM: A case of necrotising fasciitis caused by Serratia marsescens: extreme age as functional immunosuppression? Age Ageing 42: 266, 2013.
Montanaro D, Grasso GM, Annino I, et al: Epidemiological and bacteriological investigation of Serratia marcescens epidemic in a nursery and in a neonatal intensive care unit. J Hyg (Lond) 93: 67, 1984.
Cooper CL, Wiseman M, Brunham R: Bullous cellulitis caused by Serratia marcescens. Int J Infect Dis 3: 36, 1998.
Curtis CE, Chock S, Henderson T, et al: A fatal case of necrotizing fasciitis caused by Serratia marcescens. Am Surg 7: 228, 2005.
Bonner MJ, Meharg JG Jr: Primary cellulitis due to Serratia marcescens. JAMA 250: 2348, 1983.
Langrock M, Linde H, Landthaler M, et al: Leg ulcers and abscesses caused by Serratia marcescens. Eur J Dermatol 18: 705, 2008.
Carlesimo M, Pennica A, Musianese M, et al: Multiple skin ulcers due to Serratia marcescens in an immunocompetent patient. G Ital Dermatol Venereol 149: 367, 2014.
de Vries JJ, Baas WH, van der Ploeg K, et al: Outbreak of Serratia marcescens colonization and infection traced to a healthcare worker with long-term carriage on the hands. Infect Control Hosp Epidemiol 27: 1153, 2006.
Blossom D, Noble-Wang J, Su J, et al: Multistate outbreak of Serratia marcescens bloodstream infections caused by contamination of prefilled heparin and isotonic sodium chloride solution syringes. Arch Intern Med 169: 1705, 2009.
Hertle R: The family of Serratia type pore forming toxins. Curr Protein Pept Sci 6: 313, 2005.
Puvanendran R, Huey J, Pasupathy S: Necrotizing fasciitis. Can Fam Physician 55: 981, 2009.
Busch B, Ahern M, Topinka M, et al: Eschar with cellulitis as a clinical predictor in community-acquired methicillin-resistant Staphylococcus aureus (MRSA) skin abscess. J Emerg Med 38: 563, 2010.
Diaz J: The global epidemiology, syndromic classification, management, and prevention of spider bites. Am J Trop Med Hyg 71: 239, 2004.
Lipsky B, Berendt AR, Cornia PB, et al: 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections. Clin Infect Dis 54: 132, 2012.
Serratia marcescens is a ubiquitous, facultatively anaerobic, gram-negative bacillus that has been cited to cause infection in immunocompromised populations. In the literature, S marcescens infections of the lower extremity have presented as granulomatous ulceration, abscess, bullous cellulitis, and necrotizing fasciitis. Herein we present a series of three cases of lower-extremity infections in which S marcescens was the sole or a contributing pathogen. We discuss the commonalities of these three cases as well as with those previously cited. All three patients presented with some combination of a similar set of clinical characteristics, including bullae formation, liquefactive necrosis, and black necrotic eschar. All three patients were diabetic and had peripheral vascular disease.