Lemont H, Ammirati KM, Usen N: Plantar fasciitis: a degenerative process (fasciosis) without inflammation. JAPMA 93: 234, 2003
Thomas JL, Christensen JC, Kravitz SR, et al: The diagnosis and treatment of heel pain: A clinical practice guideline-revision 2010. J Foot Ankle Surg 49: S1, 2010.
Crawford F, Thomson C: Interventions for treating plantar heel pain. Cochrane Database Syst Rev 3: CD000416, 2003.
Buchbinder R: Clinical practice: Plantar fasciitis. N Engl J Med 350: 2159, 2004.
Riddle DL, Schappert SM: Volume of ambulatory care visits and patterns of care for patients diagnosed with plantar fasciitis: A national study of medical doctors. Foot Ankle Int 25: 303, 2004.
Gill LH, Kiebzak GM: Outcome of nonsurgical treatment for plantar fasciitis. Foot Ankle Int 17: 527, 1996.
Riddle DL, Pulisic M, Pidcoe P, et al: Risk factors for plantar fasciitis: A matched case-control study. J Bone Joint Surg Am 85: 872, 2003.
Tatli YZ, Kapasi S: The real risks of steroid injection for plantar fasciitis, with a review of conservative therapies. Curr Rev Musculoskelet Med 2: 3, 2009.
DiGiovanni BF, Nawoczenski DA, Malay DP, et al: Plantar fascia-specific excercise improves outcomes in patients with chronic plantar fasciitis. A prospective clinical trial with two-year follow-up. J Bone Joint Surg Am 88: 1775, 2006.
Acevedo JI, Beskin JL: Complications of plantar fascia rupture associated with corticosteroid injection. Foot Ankle Int 19: 91, 1998.
Sellman JR: Plantar fasciitis ruptura associated with corticosteroid injection. Foot Ankle Int 15: 376, 1994.
Harmon KG, Rao AL: The use of platelet-rich plasma in the nonsurgical management of sports injuries: hype or hope? Hematology Am Soc Hematol Educ Program 2013: 620, 2013.
Ragab EM, Othman AM: Platelets rich plasma for treatment of chronic plantar fasciitis. Arch Orthop Trauma Surg 132: 1065, 2012.
Martinelli N, Marinozzi A, Carni S, et al: Platelet-rich plasma injections for chronic plantar fasciitis. Int Orthop 37: 839, 2013.
Mazzocca AD, McCarthy MB, Chowaniec DM, et al: Platelet-rich plasma differs according to preparation method and human variability. J Bone Jone Srug Am 94: 308, 2012.
DeLong JM, Russell RP, Mazzocca AD: Platelet-rich plasma: The PAW classification system. Arthroscopy 28: 998, 2012
Mishra A, Pavelko T: Treatment of chronic elbow tendinosis with buffered platelet rich plasma. Am J Sport Med 34: 1774, 2006.
Fufa D, Shealy B, Jacobson M, et al: Activation of platelet-rich plasma using soluble type I collagen. J Oral Maxillofac Surg 66: 684, 2008.
Mazzucco L, Balbo V, Cattana E, et al: Not every PRP-gel is born equal: Evaluation of growth factor availability for tissues through four PRP-gel preparation. Fibrinet, RegenPRP-Kit, Plateltex and one manual procedure. Vox Sang 97: 110, 2009.
Marx RE: Platelet-rich plasma: Evidence to support its use. J Oral Maxillofac Surg 62: 489, 2004.
Eppley BL, Woodell JE, Higgins J: Platelet quantification and growth factor analysis from platelet-rich plasma: Implications for wound healing. Plast Reconstr Surg 114: 1502, 2004.
Sanchez M, Anitua E, Azofra J, et al: Comparison of surgically repaired Achilles tendon tears using platelet-rich fibrin matrices. Am J Sports Med 35: 245, 2007.
Giusti I, Rughetti A, D'Ascenzo S, et al: Identification of an optimal concentration of an optimal concentration of platelet gel for promoting angiogenesis in human endotelial cells. Transfusion 49: 771, 2009.
Huskisson EC: Measurement of pain. Lancet 2: 1127, 1974.
Martin RL, Burdett RG, Irrgang JJ: Development of the foot and ankle disability index (FADI). J Orthop Sports Phys Ther 29: A32, 1999.
Kitaoka HB, Alexander IJ, Adelaar RS, et al: Clinical rating systems for the ankle-hindfoot, midfoot, hallux, and lesser toes. Foot Ankle Int 15: 349, 1994.
O'Malley MJ, Vosseller JT, Gu Y: Successful use of platelet-rich plasma for chronic plantar fasciitis. HSS J 9: 129, 2013.
Shetty VD, Dhillon M, Hegde C, et al: A study to compare the efficacy of corticosteroid therapy with platelet-rich plasma therapy in recalcitrant plantar fasciitis: A preliminary report. Foot Ankle Surg 20: 10, 2014.
Aksahin E, Dogruyol D, Yüksel HY, et al: The comparison of the effect of corticosteroids and platelet-rich plasma (PRP) for the treatment of plantar fasciitis. Arch Orthop Trauma Surg 132: 781, 2012.
Irving DB, Cook JL, Menz HB: Factors associated with chronic plantar heel pain: a systematic review. J Sci Med Sport 9: 11, 2006.
Mishra A, Woodall J Jr, Vieira A: Treatment of tendon and muscle using platelet-rich plasma. Clin Sports Med 28: 113, 2009.
Many treatment options for plantar fasciitis currently exist, some with great success in pain relief. The objective of our study was to compare the use of intralesional steroids with platelet-rich plasma (PRP), using pain scales and functional evaluation, in patients with plantar fasciitis who did not respond to conservative treatment.
A controlled, randomized, blinded clinical assay was performed. Patients were assigned to one of the two groups by selecting a sealed envelope. The steroid treatment group received 8 mg of dexamethasone plus 2 mL of lidocaine as a local anesthetic. The PRP treatment group received 3 mL of PRP activated with 0.45 mL of 10% calcium gluconate. All of the patients were evaluated at the beginning of the study, and at 2, 4, 8, 12, and 16 weeks post-treatment with the Visual Analog Scale (VAS), Foot and Ankle Disability Index (FADI), and American Orthopedic Foot and Ankle Society (AOFAS) scale.
The right foot was the most frequently affected foot (63%). The average age of the patients was 44.8 years (range, 24–61 years). All scales used (VAS, FADI and AOFAS) showed that the difference was not statistically significant between the two groups.
We can conclude that the use of PRP is an effective treatment method for patients with plantar fasciitis who do not respond to conservative treatment because PRP demonstrates an efficacy equal to that of steroids. However, the cost and the time for preparation the PRP are two of the disadvantages of this treatment.