advertising
-
1
Abulafia J, Vignale R: Degenerative collagenous, plaques of the hands and acrokeratoelastoidosis: pathogenesis and relationship with knuckle pads. Int J Dermatol 39: 424, 2000.
-
2
Wortsman X, Alfageme F, Roustan G, et al: Guidelines for performing dermatologic ultrasound examinations by the DERMUS Group. J Ultrasound Med 35: 577, 2016.
-
3
Lewis KG, Bercovitch L, Dill SW, et al: Acquired disorders of elastic tissue: part II. Decreased elastic tissue. J Am Acad Dermatol 51: 165, 2004.
-
4
Costa OG: Akrokerato-elastoidosis (a hitherto undescribed skin disease). Dermatologica 107: 164, 1953.
-
5
Greiner J, Krüger J, Palden L, et al: A linkage study of acrokeratoelastoidosis: possible mapping to chromosome 2. Hum Genet 63: 222, 1983.
-
6
Bogle MA, Hwang LY, Tschen JA: Acrokeratoelastoidosis. J Am Acad Dermatol 47: 448, 2002.
-
7
Poiraud C, Vourch-Jourdain M, Cassagnau E, et al: Aquagenic palmoplantar keratoderma associated with acrokeratoelastoidosis. Clin Exp Dermatol 39: 671, 2014.
-
8
Tajima S, Tanaka N, Ishibashi A, et al: A variant of acrokeratoelastoidosis in systemic scleroderma: report of 7 cases. J Am Acad Dermatol 46: 767, 2002.
-
9
Klekowski N, Shwayder T: Unilateral acrokeratoelastoidosis: second reported case. Pediatr Dermatol 28: 20, 2011.
-
10
Zhai Z, Yang X, Hao F: Acrokeratoelastoidosis. Eur J Dermatol 16: 201, 2006.
-
11
Fiallo P, Pesce C, Brusasco A, et al: Acrokeratoelastoidosis of Costa: A primary disease of the elastic tissue. J Cutan Pathol 25: 580, 1998.
-
12
Rongioletti F, Betti R, Crosti C: Marginal acrokeratoelastoidosis: a unified nosography for acral hyperkeratosis, acrokeratoelastoidosis and related disorders. Dermatology 188: 28, 1994.
-
13
Rodríguez-Bandera AI, Alfageme Roldán F, Hospital-Gil M, et al: Usefulness of high-frequency ultrasound in the diagnosis of piezogenic pedal papules. Actas Dermosifiliogr. 106: 591, 2015.
-
14
Erbil H, Sezer E, Koc E, et al: Acrokeratoelastoidosis treated with the erbium:YAG laser. Clin Exp Dermatol 33: 30, 2007.
Acrokeratoelastoidosis of the Foot with Clinical, Dermoscopic, Ultrasonographic, and Histopathologic Correlation
Search for other papers by Pablo Uribe in
Current site
Google Scholar
PubMed
Search for other papers by Elena Ortiz in
Current site
Google Scholar
PubMed
Search for other papers by Ximena Wortsman in
Current site
Google Scholar
PubMed
Search for other papers by Sergio Gonzalez in
Current site
Google Scholar
PubMed
Acrokeratoelastoidosis (AKE) is a rare form of focal acral keratoderma of unknown cause that typically begins during childhood and manifests with multiple, small, hyperkeratotic papules located over the lateral margins of the hands and feet. The purpose of this article is to report a pediatric case of AKE with dermoscopic, sonographic, and histopathologic descriptions, contributing to the awareness of this clinical diagnosis. We describe a 7-year-old girl with nonpainful yellowish papules on the lateral and medial aspects of both feet. Dermoscopy showed yellowish, structureless, linear areas. The sonographic appearance was suggestive of benignancy and ruled out the presence of piezogenic pedal papules and granulomas. Histopathology was consistent with AKE, showing acral skin with hyperorthokeratosis, hypergranulosis, and elastorrhexis in the reticular dermis. Acrokeratoelastoidosis may be difficult to recognize clinically because of its resemblance to other focal acral keratodermas. Color Doppler ultrasound can be a useful noninvasive tool for diagnosis and can confirm its benign appearance, although histopathology confirms the definitive diagnosis. To date, the dermoscopic description and ultrasound morphology of AKE have not been reported.
advertising
