• 1

    Terrill PJ, Blazar P: Lipofibromatous hamartoma: a review article. Orthop J Harv Med Sch 11: 87, 2009.

  • 2

    Fares J, Natout N, Fares YJ: Neural fibrolipoma of the median nerve. J Med Liban 64: 47, 2016.

  • 3

    Aymard B, Boman-Ferrand F, Vernhes L, et al: Fibrolipomatous hamartoma of the peripheral nerves: anatomico-clinical study of 5 cases, including 2 with ultrastructural study [in French]. Ann Pathol 7: 320, 1987.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4

    Silverman TA, Enzinger FM: Fibrolipomatous hamartoma of nerve: a clinicopathologic analysis of 26 cases. Am J Surg Pathol 9: 7, 1985.

  • 5

    Kini JR, Kini H, Rau A, et al: Lipofibromatous hamartoma of the median nerve in association with or without macrodactyly. Turk Patoloji Derg 34: 87, 2018.

  • 6

    Kuo Y-L, Wu Y-H, Hsiao P-F, Hsieh J-Y: Lipofibromatous hamartoma of the superficial peroneal nerve: two case reports. Dermatol Sin 30: 21, 2012.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 7

    Dhinsa BS, Lidder S, Abbasian A: Atypical presentation of fibrolipomatous hamartoma of superficial peroneal nerve. J Foot Ankle Surg 55: 1067, 2016.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 8

    Louaste J, Zejjari H, Chkoura M, et al: Carpal tunnel syndrome due to fibrolipomatous hamartoma of the median nerve. Hand (N Y) 6: 76, 2011.

  • 9

    Agrawal R, Garg C, Agarwal A, et al: Lipofibromatous hamartoma of the digital branches of the median nerve presenting as carpal tunnel syndrome: a rare case report with review of the literature. Indian J Pathol Microbiol 59: 96, 2016.

    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 10

    Ulrich D, Ulrich F, Schroeder M, et al: Lipofibromatous hamartoma of the median nerve in patients with macrodactyly: diagnosis and treatment of a rare disease causing carpal tunnel syndrome. Arch Orthop Trauma Surg 129: 1219, 2009.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 11

    Taddie KL, Fallat LM: Lipofibromatous hamartoma of nerve. J Foot Ankle Surg 46: 116, 2007.

  • 12

    Hirakawa E, Miki H, Kobayashi S, et al: Lipofibromatous hamartoma of nerve in the foot. Acta Pathol Jpn 43: 265, 1993.

  • 13

    Naik G, Mitra D, Shetty S, et al: A case report of neural fibrolipoma of foot. J Med Sci Health 2: 41, 2016.

  • 14

    Akisue T, Matsumoto K, Yamamoto T, et al: Neural fibrolipoma of the superficial peroneal nerve in the ankle: a case report with immunohistochemical analysis. Pathol Int 52: 730, 2002.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15

    Krzywosinski TB, Bingham AL, Fallat LM: Intraneural lipoma of the tibial nerve: a case report. J Foot Ankle Surg 56: 125, 2016.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 16

    Donley BG, Neel M, Mitias HM: Neural fibrolipoma of the foot: a case report. Foot Ankle Int 17: 712, 1996.

  • 17

    Zeng R, Frederick-Dyer K, Ferguson NL, et al: Fibrolipomatous hamartoma of the inferior calcaneal nerve (Baxter nerve). Skeletal Radiol 41: 1323, 2012.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 18

    Fandridis EM, Kiriako AS, Spyridonos SG, et al: Lipomatosis of the sciatic nerve: report of a case and review of the literature. Microsurgery 29: 66, 2009.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 19

    Van Breuseghem I, Sciot R, Pans S, et al: Fibrolipomatous hamartoma in the foot: atypical MR imaging findings. Skeletal Radiol 32: 651, 2003.

  • 20

    Parihar A, Verma S, Senger M, et al: Fibrolipomatous hamartoma of sural nerve: a new site of an unusual lesion. Malays J Pathol 36: 59, 2014.

  • 21

    Mam P, Lewis EB, Song T, et al: Fibrolipomatous hamartoma of nerve in the great toe. JAPMA 104: 531, 2014.

  • 22

    Fransen BL, Broeders MG, van Oosterom FJ, et al: Operative resection is a viable treatment of macrodactyly of the foot caused by lipofibromatous hamartoma: a case study with 5 year follow-up. Foot Ankle Surg 20: e47, 2014.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation

Lipofibromatous Hamartoma of the Plantar Nerve

An Extremely Rare Localization

Murat Mert Department of Orthopaedics and Traumatology, Yeni Yuzyıl University Medical Faculty, Istanbul, Turkey.

Search for other papers by Murat Mert in
Current site
Google Scholar
PubMed
Close
 MD
and
Payam Hacısalihoglu Department of Pathology, Yeni Yuzyıl University Medical Faculty, Istanbul, Turkey.

Search for other papers by Payam Hacısalihoglu in
Current site
Google Scholar
PubMed
Close
 MD

Lipofibromatous hamartoma (LFH) is a rare, benign, tumor-like soft-tissue lesion that affects the peripheral nerves and forms a palpable neurogenic mass. Lipofibromatous hamartoma is associated with pain and sensory and/or motor deficits in the area of innervation of the affected nerve. This report describes a rare case of LFH of the plantar nerve. A 48-year-old woman presented to our outpatient orthopedic clinic with pain and a burning sensation on her left foot. The patient had a history of Morton's neuroma and had undergone a tarsal tunnel operation 2 years earlier at another center. None of her symptoms was alleviated by two previous operations. Magnetic resonance imaging with contrast revealed tenosynovitis of the flexor hallucis longus tendon and signal changes at deep tissue planes of the foot at the levels of the second and third toes, on the dorsal site and subcutaneous soft-tissue planes, suggesting edema and Morton's neuroma. The lesion was excised under spinal anesthesia, and histopathologic examination of the specimen revealed a diagnosis of LFH. The patient was discharged without any symptoms and her foot was normal at 8-month outpatient follow-up, with no indications of postoperative complications and/or recurrence.

Corresponding author: Murat Mert, MD, Department of Orthopaedics and Traumatology, Yeni Yuzyıl University Medical Faculty, Ozel GOP hastanesi, merkez mah. cukurcesme c. N: 5 Gaziosmanpasa, Istanbul, 34245, Turkey. (E-mail: muratmertdr@gmail.com)
Save