• 1

    Szepietowski JC. Salomon J. Do fungi play a role in psoriatic nails? Mycoses 50: 437, 2007.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 2

    Yenişehirli G. Bulut Y. Sezer E. et al: Onychomycosis infections in the Middle Black Sea Region, Turkey. Int J Dermatol 48: 956, 2009.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 3

    Greer DL. Evolving role of nondermatophytes in onychomycosis. Int J Dermatol 34: 521, 1995.

  • 4

    Elewski BE. Charif MA. Prevalence of onychomycosis in patients attending a dermatology clinic in northeastern Ohio for other conditions. Arch Dermatol 133: 1172, 1997.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5

    Westerberg DP. Voyack MJ. Onychomycosis: current trends in diagnosis and management. Am Fam Physician 88: 762, 2013.

  • 6

    Martínez-Herrera EO. Arroyo-Camarena S. Tejada-García DL. et al: Onychomycosis due to opportunistic molds. An Bras Dermatol 90: 334, 2015.

  • 7

    Das NK. Ghosh P. Das S. et al: A study on the etiological agent and clinico-mycological correlation of fingernail onychomycosis in eastern India. Indian J Dermatol 53: 75, 2008.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 8

    Gupta M. Sharma NL. Kanga AK. et al: Onychomycosis: clinic-mycologic study of 130 patients from Himachal Pradesh, India. Indian J Dermatol Venereol Leprol 73: 389, 2007.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9

    Sanjiv A. Shalini M. Charoo H. Etiological agents of onychomycosis from a tertiary care hospital in Central Delhi, India. Indian J Fund Appl Life Sci 1: 11, 2011.

    • Search Google Scholar
    • Export Citation
  • 10

    Adekhandi S. Pal S. Sharma N. et al: Incidence and epidemiology of onychomycosis in patients visiting a tertiary care hospital in India. Cutis 95: E20, 2015.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11

    Borman AM. Campbell CK. Fraser M. et al: Analysis of the dermatophyte species isolated in the British Isles between 1980 and 2005 and review of worldwide dermatophyte trends over the last three decades. Med Mycol 45: 131, 2007.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 12

    Morales CA. Solórzano A. Rojas AP. Características epidemiológicas y clínicas de las onicomicosis causadas por Fusarium spp. en un centro de referencia de Bógota, Colombia, 2001-2010. Rev Asoc Colomb Dermatol 21: 21, 2013.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 13

    Tosti A. Piraccini BM. Lorenzi S. Onychomycosis caused by nondermatophytic molds: clinical features and response to treatment of 59 cases. J Am Acad Dermatol 42: 217, 2000.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14

    Han MH. Choi JH. Sung KJ. et al: Onychomycosis and Trichosporon beigelii in Korea. Int J Dermatol 39: 266, 2000.

  • 15

    Magalhães AR. Nishikawa MM. Mondino SS. et al: Trichosporon isolation from human ungueal infections: is there a pathogenic role? An Bras Dermatol 91: 173, 2016.

    • Crossref
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 16

    Gunduz T. Metin DY. Sacar T. et al: Onychomycosis in primary school children: association with socioeconomic conditions. Mycoses 49: 431, 2006.

  • 17

    Moreno G. Arenas R. Other fungi causing onychomycosis. Clin Dermatol 28: 160, 2010.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 18

    Blake N. Zhu J. Hernandez G. et al: A retrospective review of diagnostic testing for onychomycosis of the foot. JAPMA 105: 503, 2015.

Etiology of Onychomycosis in Patients in Turkey

View More View Less
  • 1 Department of Dermatology, Bezmialem Vakif University, Istanbul, Turkey.
  • | 2 Department of Dermatology, Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
Restricted access

Background:

Onychomycosis is a chronic nail infection caused by dermatophytes, Candida, nondermatophyte molds, and Trichosporon. The purpose of this study was to identify the underlying pathogen in patients with onychomycosis in our region.

Methods:

A retrospective analysis of 225 cases with onychomycosis, diagnosed over a 27-month period at the Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey, and confirmed with culture, was performed.

Results:

Patient age ranged from 2 to 87 years (mean ± SD, 41.59 ± 17.61), and female patients were more commonly affected (120 cases, 53.3%) than male patients. Lateral and distal subungual onychomycosis was detected in 180 cases (80%). Etiologic agents were as follows: Trichophyton rubrum, 77 cases (34.2%); Trichophyton mentagrophytes, 30 cases (13.3%), Candida albicans, 28 cases (12.4%); Candida parapsilosis, 25 cases (11.1%); Acremonium species, one case (0.4%); Aspergillus species, two cases (0.9%); Fusarium species, four cases (1.3%); and Trichosporon species, three cases (1.3%).

Conclusions:

The most frequent isolated etiologic agents were T rubrum for toenails and C albicans for fingernails.

Corresponding author: Fatma Pelin Cengiz, MD, Department of Dermatology, Bezmialem Vakif University, 34710 Istanbul, Turkey. (E-mail: fpelinozgen@hotmail.com)