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Podiatric Adverse Events and Foot Care in Cancer Patients and Survivors

Awareness, Education, and Literature Review

Mario E. Lacouture Memorial Sloan Kettering Cancer Center, New York, NY.

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David J. Kopsky Institute for Neuropathic Pain, Amsterdam, the Netherlands.

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Raphael Lilker Coney Island Hospital, Brooklyn, NY.

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Fiona Damstra Reade Rehabilitation Centre, Amsterdam, the Netherlands.

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Mecheline H.M. van der Linden VUMC University Medical Center, Amsterdam, the Netherlands.

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Azael Freites-Martinez Memorial Sloan Kettering Cancer Center, New York, NY.

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Mischa P.M. Nagel Medische Voet and Supplement, Amsterdam, the Netherlands.

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Cancer is one of the leading causes of mortality and morbidity worldwide. Recent improved therapies have resulted in more patients surviving cancer and living longer. Despite these advances, the majority of patients will develop adverse events from anticancer therapies. Foot alterations, including nail toxicities, hand-foot syndrome, edema, xerosis, hyperkeratosis, and neuropathy, are frequent among cancer patients. These untoward conditions may negatively impact quality of life, and in some cases may result in the interruption or discontinuation of cancer treatments. Appropriate prevention, diagnosis, and management of podiatric adverse events are essential to maintain foot function and health-related quality of life, both of which are critical for the care of cancer patients and survivors. This article shows results related to complaint and impact on quality of life of the Oncology Foot Care program and reviews publications specific to podiatric adverse events related to cancer treatments.

Corresponding author: Mischa P.M. Nagel, BS, Foundation for Foot Oncology, Amstelveenseweg 970 C, 1081 JR Amsterdam, the Netherlands. (E-mail: mischa@mischanagel.nl)