• 1.

    Mangrulka V , Brunetti V & Gould E et al.: Unusually large pedal schwannoma. J Foot Ankle Surg 46 : 398, 2007.

  • 2.

    Albert P , Patel J & Badway K et al.: Peripheral nerve schwannoma: a review of varying clinical presentations and imaging findings. J Foot Ankle Surg 56 : 632, 2017.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 3.

    Kim DH , Murovich JA & Tiel RL et al.: A series of 397 peripheral neural sheath tumors: 30-year experience at Louisiana State University Health Sciences Center. J Neurosurg 102 : 246, 2005.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4.

    Das DK: Psammoma body: a product of dystrophic calcification or of a biologically active process that aims at limiting the growth and spread of tumor? Diagn Cytopathol 37 : 534, 2009.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 5.

    Merat R , Szalay-Quinodoz I & Laffitte E et al.: Psammomatous melanotic schwannoma: a challenging histological diagnosis. Dermatopathology (Basel) 2 : 67, 2015.

  • 6.

    Kaltsas G & Kanakis G: Carney complex. Endotext. Available at: https://www.ncbi.nlm.nih.gov/books/NBK279117/. Accessed November 18, 2018.

  • 7.

    US National Library of Medicine: Carney complex. Available at: https://ghr.nlm.nih.gov/condition/carney-complex. Accessed December 2, 2018.

  • 8.

    Kirschner LS , Carney JA & Pack SD et al.: Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with Carney complex. Nat Genet 26 : 89, 2000.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9.

    National Organization for Rare Disorders: Carney complex. Available at: https://rarediseases.org/rare-diseases/carney-complex/. Accessed December 2, 2018.

  • 10.

    Tangella K. Melanotic schwannoma. Available at: https://www.dovemed.com/diseases-conditions/melanotic-schwannoma/. Accessed December 6, 2018.

  • 11.

    Schaberg K , Born D & Rouse R: Surgical pathology criteria. Available at: http://surgpathcriteria.stanford.edu/peripheral-nerve/schwannoma/. Accessed November 23, 2018.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12.

    Zuckerman JD , Powers B & Miller JW et al. Benign solitary schwannoma of the foot: a case report and review of literature. Clin Orthop Relat Res 228 : 278, 1988.

  • 13.

    Carney AJ. Psammomatous melanocytic schwannoma. A distinctive, heritable tumor with special associations including cardiac myxoma and the Cushing syndrome. Am J Surg Pathol 14 : 206, 1990.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14.

    Ly P. Solitary benign schwannoma of the foot presenting clinically as a ganglion cyst: a case study. JAPMA 108 : 340, 2018.

  • 15.

    Pasternack WA & Winter-Reiken DJ: Unusually large cellular schwannoma of the foot. JAPMA 95 : 157, 2005.

Schwannoma with Psammoma Body

Lindsay M. Hummel
Search for other papers by Lindsay M. Hummel in
Current site
Google Scholar
PubMed
Close
 DPM
,
Susan Gamble
Search for other papers by Susan Gamble in
Current site
Google Scholar
PubMed
Close
 DPM
,
Robert Krouse
Search for other papers by Robert Krouse in
Current site
Google Scholar
PubMed
Close
 MD
,
Darshana Jhala
Search for other papers by Darshana Jhala in
Current site
Google Scholar
PubMed
Close
 MD
,
Sharvari Dalal
Search for other papers by Sharvari Dalal in
Current site
Google Scholar
PubMed
Close
 MD
, and
Opoku Adjapong
Search for other papers by Opoku Adjapong in
Current site
Google Scholar
PubMed
Close
 MD

We present a case of a 59-year-old male veteran with a chronic history of right foot soft-tissue mass that was causing pain in his shoes, but not functional or neurologic symptoms. Excision of the mass and pathologic evaluation resulted in multidisciplinary involvement and evaluation. In this example, the mass was found to be either an unusual schwannoma that happens to be psammoma body–rich or an unusual psammomatous melanocytic schwannoma that deviates from conventional examples, as a diagnostic consensus was unable to be reached. Schwannomas are an uncommon finding in the foot, and even more uncommon are those that contain psammoma bodies. Although rare, these tumors can be concerning for more systemic, life-altering diseases such as Carney complex, for which our patient refused genetic testing.

Philadelphia Veterans Affairs Medical Center, Philadelphia, PA. Dr. Hummel is now with Hummel Foot and Ankle LLC, Mechanicsburg, PA.

Corresponding author: Lindsay M. Hummel, DPM, 161 Old Schoolhouse Lane, Mechanicsburg, PA 17055. (E-mail: lindsayhummel@ymail.com)
Save