• 1. 

    Bakotic B & Huvos A: Tumors of the bones of the feet: the clinicopathologic features of 150 cases. J Foot Ankle Surg 40 : 277, 2001.

  • 2. 

    Ozdemir HM , Yilmaz C & Yildiz Y et al.: Tumors of the foot and ankle: analysis of 196 cases. J Foot Ankle Surg 36 : 403, 1997.

  • 3. 

    Ruggieri P , Angelini A & Jorge FD et al.: Review of foot tumors seen in a university tumor institute. J Foot Ankle Surg 53 : 282, 2014.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 4. 

    Boccadoro M & Pileri A: Plasma cell dyscrasias: classification, clinical and laboratory characteristics, and differential diagnosis. Baillieres Clin Haematol 8 : 705, 1995.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5. 

    Kyle RA: Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol 121 : 749, 2003.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6. 

    Agarwal A & Ghobrial IM: Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma: a review of the current understanding of epidemiology, biology, risk stratification, and management of myeloma precursor disease. Clin Cancer Res 19 : 985, 2013.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 7. 

    Kyle RA , Therneau TM & Rajkumar SV et al.: Prevalence of monoclonal gammopathy of undetermined significance. N Engl J Med 354 : 1362, 2006.

  • 8. 

    Landgren O , Kyle RA & Pfeiffer RM et al.: Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study. Blood 113 : 5412, 2009.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 9. 

    Aggarwal S , Goulatia RK & Sood A et al.: POEMS syndrome: a rare variety of plasma cell dyscrasia. AJR Am J Roentgenol 155 : 339, 1990.

  • 10. 

    Khoddami M & Fernandes BJ: Solitary IgA myeloma of the foot. A case report and review of the literature. JAPMA 87 : 233, 1997.

  • 11. 

    Saviet BM , Marcoux JT & Narayanasami U: Rare pedal manifestation of diffuse multiple myeloma lesions. J Foot Ankle Surg 56 : 357, 2017.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 12. 

    Solimando AG , Sportelli A & Troiano T et al.: A multiple myeloma that progressed as type I cryoglobulinemia with skin ulcers and foot necrosis. A case report. Medicine (Baltimore) 97 : e12355, 2018.

    • Crossref
    • PubMed
    • Web of Science
    • Search Google Scholar
    • Export Citation
  • 13. 

    Wikipedia. Calcium alginate. Available at: https://en.wikipedia.org/w/index.php?title=Calcium_alginate&oldid=914213068. Accessed September 5, 2019.

Plasma Cell Dyscrasia of the Calcaneus: A Rare and Unusual Case Presentation

Peter N. Ly
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A rare and unusual case of plasma cell dyscrasia of the calcaneus is presented. Clinically, the patient had a draining and painful ulcer that was treated with appropriate antibiotics and wound care but failed to show any signs of healing. Radiographic images showed cystic changes of the calcaneus in the vicinity of the ulcer. Blood work was negative for bone and soft-tissue infection, but uric acid and alkaline phosphatase levels were elevated. Nuclear bone scan showed increased uptake in the calcaneus suggestive of osteomyelitis. One possible differential diagnosis was an intraosseous gouty tophus deposit. Not convinced that this was either a bone infection or gout, the author performed a bone biopsy. Pathologic evaluation indicated plasma cell dyscrasia. Continued wound care healed the ulcer completely, with resolution of pain of his heel. Oncology/hematology was consulted, and 16 months after biopsy, he remains asymptomatic.

VA Central California Health Care System, Surgical Service 112, 2615 East Clinton Ave, Fresno, CA 93703-2223. (E-mail: peter.ly@va.gov)

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