• 1. 

    Driver VR , Fabbi M & Lavery LA et al.: The costs of diabetic foot: the economic case for the limb salvage team. JAPMA 100 : 335, 2010.

  • 2. 

    American Diabetes Association: Economic costs of diabetes in the U.S. in 2012. Diabetes Care 36 : 1033, 2013.

  • 3. 

    Attinger CE , Hoang H & Steinberg J et al.: How to make a hospital-based wound center financially viable: the Georgetown University Hospital model. Gynecol Oncol 111 (suppl) : S92, 2008.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4. 

    Cavanagh P , Attinger C & Abbas Z et al.: Cost of treating diabetic foot ulcers in five different countries. Diabetes Metab Res Rev 28 (suppl 1) : 107, 2012.

  • 5. 

    Ragnarson Tennvall G & Apelqvist J : Health-economic consequences of diabetic foot lesions. Clin Infect Dis 39 (suppl 2) : S132, 2004.

  • 6. 

    Sumpio BE , Lee T & Blume PA: Vascular evaluation and arterial reconstruction of the diabetic foot. Clin Podiatr Med Surg 20 : 689, 2003.

  • 7. 

    Faries PL , Teodorescu VJ & Morrissey NJ et al.: The role of surgical revascularization in the management of diabetic foot wounds. Am J Surg 187 : 34S, 2004.

  • 8. 

    Muhs BE , Gagne P & Sheehan P: Peripheral arterial disease: clinical assessment and indications for revascularization in the patient with diabetes. Curr Diab Rep 5 : 24, 2005.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9. 

    Prompers L , Schaper N & Apelqvist J et al.: Prediction of outcome in individuals with diabetic foot ulcer: focus on the differences between individuals with and without peripheral arterial disease: the EURODIALE Study. Diabetologia 51 : 747, 2008.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10. 

    Hinchliffe RJ , Forsythe RO & Apelqvist J et al.: Guidelines on diagnosis, prognosis, and management of peripheral artery disease in patients with foot ulcers and diabetes (IWGDF 2019 update). Diabetes Metab Res Rev 36 (Suppl 1) : e3276, 2020.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11. 

    Allen L , Powell-Cope G & Mbah A et al.: A retrospective review of adverse events related to diabetic foot ulcers. Ostomy Wound Manage 63 : 30, 2017.

  • 12. 

    Hay JW , Lawler E & Yucel K et al.: Cost impact of diagnostic imaging for lower extremity peripheral vascular occlusive disease. Value Health 12 : 262, 2009.

  • 13. 

    Mohan B , Mohan G & Tandon R et al.: A cost effective endovascular approach for management of post-catheterization profunda femoris artery pseudoaneurysm using thrombin. Indian Heart J 66 : 83, 2014.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14. 

    Barshes NR , Flores E & Belkin M et al.: The accuracy and cost-effectiveness of strategies used to identify peripheral artery disease among patients with diabetic foot ulcers. J Vasc Surg 64 : 1682, 2016.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15. 

    Schwartz RD , Rubin JE & Leeming RW et al.: Renal failure following major angiography. Am J Med 60 : 31, 1978.

  • 16. 

    Cronin RE: Renal failure following radiologic procedures. Am J Med Sci 298 : 342, 1989.

  • 17. 

    Osten MD , Ivanov J & Eichhofer J et al.: Impact of renal insufficiency on angiographic, procedural, and in-hospital outcomes following percutaneous coronary intervention. Am J Cardiol 101 : 780, 2008.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 18. 

    Tehrani S , Laing C & Yellon DM et al.: Contrast-induced acute kidney injury following PCI. Eur J Clin Invest 43 : 483, 2013.

  • 19. 

    Prasad A , Ortiz-Lopez C & Khan A et al.: Acute kidney injury following peripheral angiography and endovascular therapy: a systematic review of the literature. Catheter Cardiovasc Interv 88 : 264, 2016.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 20. 

    Louvel JP , Czernichow P & Kervarrec Y et al.: Inter-observer variability in the interpretation of arteriographies of the carotid arteries and lower limbs. J Radiol 65 : 673, 1984.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 21. 

    Slot HB , Strijbosch L & Greep JM: Interobserver variability in single-plane aortography. Surgery 90 : 497, 1981.

  • 22. 

    White C: Clinical practice: intermittent claudication. N Engl J Med 356 : 1241, 2007.

  • 23. 

    Mustapha JA , Diaz-Sandoval L & Saab F: Infrapopliteal calcification patterns in critical limb ischemia: diagnostic pathologic and therapeutic implications in the search for the endovascular holy grail. J Cardiovasc Surg (Torino) 58 : 383, 2017.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 24. 

    Kashyap VS , Pavkov ML & Bishop PB et al.: Angiography underestimates peripheral atherosclerosis: lumenography revisited. J Endovasc Ther 15 : 117, 2008.

  • 25. 

    Attinger CE , Evans KK & Bulan E et al.: Angiosomes of the foot and ankle and clinical implications for limb salvage: reconstruction, incisions, and revascularization. Plast Reconstr Surg 117 (suppl) : 261S, 2006.

    • Crossref
    • PubMed
    • Search Google Scholar
    • Export Citation
  • 26. 

    Clemens MW & Attinger CE: Angiosomes and wound care in the diabetic foot. Foot Ankle Clin 15 : 439, 2010.

  • 27. 

    Attinger CE , Meyr AJ & Fitzgerald S et al.: Preoperative Doppler assessment for transmetatarsal amputation. J Foot Ankle Surg 49 : 101, 2010.

Level of Agreement Between Systematic Doppler Examination of the Lower Extremity and Diagnostic Angiography in the Setting of Peripheral Arterial Disease

Timothy Greene
Search for other papers by Timothy Greene in
Current site
Google Scholar
PubMed
Close
 DPM
,
Todd Hasenstein
Search for other papers by Todd Hasenstein in
Current site
Google Scholar
PubMed
Close
 DPM
,
Eric T. Choi
Search for other papers by Eric T. Choi in
Current site
Google Scholar
PubMed
Close
 MD
, and
Andrew J. Meyr
Search for other papers by Andrew J. Meyr in
Current site
Google Scholar
PubMed
Close
 DPM

Background

The objective of this investigation was to determine the level of agreement between a systematic clinical Doppler examination of the foot and ankle and diagnostic peripheral angiography.

Methods

The described Doppler examination technique attempted to determine the patency, quality, and direction of the flow through the dorsalis pedis artery, posterior tibial artery, terminal branches of the peroneal artery, and vascular arch of the foot. These results were then compared with angiographic distal run-off images as interpreted by a blinded vascular surgeon.

Results

Levels of agreement with respect to artery patency/quality ranged from 64.0% to 84.0%. Sensitivity ranged from 53.8% to 84.2%, and specificity ranged from 64.7% to 91.7%. Agreement with respect to arterial flow direction ranged from 73.3% to 90.5%.

Conclusions

We interpret these results to indicate that this comprehensive physical examination technique of the arterial flow to the foot and ankle with a Doppler device might serve as a reasonable initial surrogate to diagnostic angiography in some patients with peripheral arterial disease.

Temple University Hospital Podiatric Surgical Residency Program, Philadelphia, PA.

Department of Vascular Surgery, Temple University School of Medicine, Philadelphia, PA.

Department of Podiatric Surgery, Temple University School of Podiatric Medicine, Philadelphia, PA.

Corresponding author: Andrew J. Meyr, DPM, Department of Podiatric Surgery, Temple University School of Podiatric Medicine, 8th at Race Street, Philadelphia, PA 19107. (E-mail: ajmeyr@gmail.com)
Save