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Heel Spur and Radiotherapy: Case Report and Systematic Literature Review

Antonio Piras Unità Operativa Radioterapia Oncologica, Villa Santa Teresa, Bagheria, Palermo, Italy.

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Luca Boldrini Unità Operativa Complessa Radioterapia Oncologica - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Rome, Italy.
Università Cattolica del Sacro Cuore, Rome, Italy.

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Calogero Rinaldi Unità Operativa Fisica Sanitaria, Villa Santa Teresa, Bagheria, Palermo, Italy.

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Antonella Sanfratello Università degli Studi di Palermo, Radioterapia Oncologica, Palermo, Italy.

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Andrea D’Aviero Unità Operativa Complessa Radioterapia Oncologica - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Rome, Italy.

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Angelo Toscano General Orthopaedic Surgery, Rizzoli-Sicilia Department, Rizzoli Orthopaedic Institute, Bagheria, Palermo, Italy.

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Tommaso Angileri Unità Operativa Radiologia, Villa Santa Teresa, Bagheria, Palermo, Italy.

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Massimiliano Spada Unità Operativa Oncologia, Fondazione Istituto G. Giglio, Cefalù, Palermo, Italy.

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Antonino Daidone Unità Operativa Radioterapia Oncologica, Villa Santa Teresa, Bagheria, Palermo, Italy.

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Heel spur is a chronic inflammatory condition causing pain and other typical symptoms. Therapeutic recommendations include the use of several drug or orthotic/physical therapies, performed alone or in combination. Surgery is usually reserved for refractory conditions. Radiotherapy has been shown to ensure good clinical outcomes in this clinical setting. A systematic review was performed to describe the feasibility and effectiveness of radiotherapy in the treatment of heel spur, evaluating its role in alleviating pain and consequently ensuring a better quality of life. A case report of 45-year-old patient treated for refractary right hindfoot pain was reported. A single fraction of 6 Gy RT was delivered with symptomatic complete response at 2 months observed. A systematic database search was conducted according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines. The systematic review included studies describing heel spur treatment and providing complete information about radiotherapy. Fifteen articles published between 1996 and 2020 were reviewed. Study characteristic analysis resulted in seven prospective randomized studies and eight retrospective studies. Radiotherapy of painful heel spur seems to be safe and effective, with high response rates even at low doses and with an overall favorable toxicity profile. Predictive parameters and modern tailored treatment should be investigated with further studies.

Corresponding author: Andrea D’Aviero, MD, UOC Radioterapia Oncologica - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Roma. (E-mail: andrea.daviero@guest.policlinicogemelli.it)
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