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Decreasing Osteomyelitis Occurrence in Remaining Bone After Partially Resected Infected Bone

Jeffrey C. Karr The Osteomyelitis Center of Central Florida, 5421 S Florida Ave, Lakeland, FL 33813

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Background: After partial bone resection for osteomyelitis there is a high rate of osteomyelitis occurrence in the remaining bone due to adherent bacterial biofilm, dysvascular infected spongiosum bone, and absence of a surgical technique that can prevent osteomyelitis developing in the remaining bone.

Methods: Presented is a surgical procedure using a dicalcium phosphate bone void filler putty with antibiotics placed into the remaining bone to prevent the development of osteomyelitis, therefore preventing amputation.

Results: This procedure has an osteomyelitis eradication rate of 94.8% and also decreases the rate of lower-extremity amputations.

Conclusions: This procedure provides a single stage surgical technique for infected open bone defects decreasing the previously reported high osteomyelitis reoccurrence rate of 57.1% to 5.2%.

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