Benedetto AV: Botulinum Toxin in Clinical Dermatology, Taylor & Francis, London, 2006.
Thomas S, Brown J, Vafaie J, et al.: Palmoplantar hyperhidrosis: a therapeutic challenge. Am Fam Physician 69: 1117, 2004.
Gorelick J, Friedman A: Diagnosis and management of primary hyperhidrosis: practical guidance and current therapy update. J Drugs Dermatol 19: 217, 2020.
Glaser DA, Hebert A, Pieretti L, et al.: Understanding patient experience with hyperhidrosis: a national survey of 1,985 patients. J Drugs Dermatol 17: 392, 2018.
Lenefsky M, Rice ZP: Hyperhidrosis and its impact on those living with it. Am J Manag Care 24 (suppl): S491, 2018.
Lowe NJ, Glaser DA, Eadie N, Daggett S, Kowalski JW, Lai PY; North American Botox in Primary Axillary Hyperhidrosis Clinical Study Group: Botulinum toxin type A in the treatment of primary axillary hyperhidrosis: a 52-week multicenter double-blind, randomized, placebo-controlled study of efficacy and safety. J Am Acad Dermatol 56: 604, 2007; doi: 10.1016/j.jaad.2007.01.009. Epub 2007 Feb 15.
Champion RH: “Disorder of Sweat Glands,” in Text Book of Dermatology, 5th ed, Vol 3, edited by RH Champion, JL Burton, FJH Ebling, p 1752, Blackwell Scientific Publications, Oxford, 1993.
Heckmann M: Complications in patients with palmar hyperhidrosis treated with transthoracic endoscopic sympathectomy. Neurosurgery 42: 1403, 1998.
Siah TW, Hampton PJ: The effectiveness of tap water iontophoresis for palmoplantar hyperhidrosis using a Monday, Wednesday, and Friday treatment regime. Dermatol Online J 19: 14, 2013.
Hölzle E, Hund M, Lommel K, et al.: Recommendations for tap water iontophoresis. J Dtsch Dermatol Ges 8: 379, 2010.
Stolman LP: Hyperhidrosis: medical and surgical treatment. Eplasty 8: e22, 2008.
Gollins CE, Carpenter A, Steen C, et al.: A retrospective analysis of the use of tap water iontophoresis for focal hyperhidrosis at a district general hospital: the patients' perspective. J Dermatolog Treat 30: 724, 2019; doi: 10.1080/09546634.2019.1569751. Epub 2019 Jun 20.
DeLisa JA, Walsh NE. Physical Medicine and Rehabilitation: Principles and Practice, Lippincott Williams & Wilkins, Philadelphia, 2005.
Solish N, Bertucci V, Dansereau A, et al.: A comprehensive approach to the recognition, diagnosis, and severity-based treatment of focal hyperhidrosis: recommendations of the Canadian Hyperhidrosis Advisory Committee. Dermatol Surg 33: 908, 2007.
Kowalski JW, Eadie N, Dagget S, et al.: Validity and reliabilty of the Hyperhidrosis Disease Severity Scale (HDSS). J Am Acad Dermatol 50: 51, 2006.
Levit F: Treatment of hyperhidrosis by tap water iontophoresis. Cutis 26: 192, 1980.
Haider A, Solish N, Lowe NJ: Management of hyperhidrosis. Available at: http://www.sweatclinicsofcanada.com/Book.pdf. Accessed September 14, 2019.
Moraites E, Vaughn OA, Hill S: Incidence and prevalence of hyperhidrosis. Dermatol Clin 32: 457, 2014.
Stolman LP: Treatment of excess sweating of the palms by iontophoresis. Arch Dermatol 123: 893, 1987.
Background: The purpose of this study was to evaluate the effectiveness of tap water iontophoresis as a treatment for plantar hyperhidrosis.
Methods: Thirty participants living with idiopathic plantar hyperhidrosis and consented to undergo treatment using iontophoresis were recruited. The Hyperhidrosis Disease Severity Score was used to evaluate the severity of the condition before and after treatment.
Results: Tap water iontophoresis was found to be effective in the treatment of plantar hyperhidrosis in the study group (P = .005).
Conclusions: Treatment with iontophoresis led to the reduction of disease severity and improvement of quality of life, and it is a safe, easy-to-use method with minimal side effects. This technique should be considered before the use of systemic or aggressive surgical interventions, which could have potentially more severe side effects.