• 1

    Steinbrink JM, Miceli MH: Mucormycosis. Infect Dis Clin North Am 35: 435, 2021.

  • 2

    Skiada A, Lass-Floerl C, Klimko N, et al: Challenges in the diagnosis and treatment of mucormycosis. Med Mycol 56(suppl 1): 93, 2018.

  • 3

    Hibbett DS, Binder M, Bischoff JF, et al: A higher-level phylogenetic classification of the fungi. Mycol Res 111: 509, 2007.

  • 4

    Petrikkos G, Skiada A, Lortholary O, et al: Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis 54(suppl 1): S23, 2012.

  • 5

    Castrejón-Pérez AD, Welsh EC, Miranda I, et al: Cutaneous mucormycosis. An Bras Dermatol 92: 304, 2017.

  • 6

    Pal R, Singh B, Bhadada SK, et al: COVID-19-associated mucormycosis: an updated systematic review of literature. Mycoses 64: 1452, 2021.

  • 7

    Roden MM, Zaoutis TE, Buchanan WL, et al: Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 41: 634, 2005.

  • 8

    Agrawal R, Yeldandi A, Savas H, et al: Pulmonary mucormycosis: risk factors, radiologic findings, and pathologic correlation. Radiographics 40: 656, 2020.

  • 9

    Luo Z, Zhang L: Diagnosis and treatment of pulmonary mucormycosis: a case report. Exp Ther Med 14: 3788, 2017.

  • 10

    Lewis RE, Kontoyiannis DP: Epidemiology and treatment of mucormycosis. Future Microbiol 8: 1163, 2013.

  • 11

    Spellberg B, Edwards J Jr, Ibrahim A: Novel perspectives on mucormycosis: pathophysiology, presentation, and management. Clin Microbiol Rev 18: 556, 2005.

Black Fungus of the Foot: An Unusual Presentation of COVID-19–Associated Mucormycosis

Ashley T. Russo Department of Orthopedic Surgery, Division of Podiatry, NYU Grossman Long Island School of Medicine, Mineola, NY.

Search for other papers by Ashley T. Russo in
Current site
Google Scholar
PubMed
Close
 DPM, MS
,
Raffaella Buffolino Department of Orthopedic Surgery, Division of Podiatry, NYU Grossman Long Island School of Medicine, Mineola, NY.

Search for other papers by Raffaella Buffolino in
Current site
Google Scholar
PubMed
Close
 DPM
,
Marianna Shvartsbeyn The Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, NY.

Search for other papers by Marianna Shvartsbeyn in
Current site
Google Scholar
PubMed
Close
 MD
, and
Shane A. Meehan The Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, NY.

Search for other papers by Shane A. Meehan in
Current site
Google Scholar
PubMed
Close
 MD

Mucormycosis, also known as black fungus, is a rare but aggressive fungal disease with high morbidity and mortality rates that tends to affect patients who are severely immunocompromised. Early recognition of the infection and prompt intervention is critical for treatment success. In recent years the coronavirus disease of 2019 (COVID-19) pandemic has resulted in a surge in the number of cases of mucormycosis. This study aims to report an unfortunate event involving an immunocompromised elderly man with mucormycosis of the foot who died as a result of sepsis caused by COVID-19. It is important to have a high clinical suspicion for mucormycosis when a clinical lesion develops, and to appropriately perform biopsy the lesion in question, particularly in the context of COVID-19. Raising awareness of COVID-19–associated mucormycosis may allow for early detection of the disease, thus enabling the initiation of rapid treatment, ultimately saving lives.

Corresponding author: Ashley T. Russo, DPM, MS, Department of Orthopedic Surgery, Division of Podiatry, NYU Grossman Long Island School of Medicine, 222 Station Plaza N, Ste 305, Mineola, NY 11501. (E-mail: ashley.russo@nyulangone.org)
Save