• 1.

    Larralde M, Giachetti A, Cáceres MR, et al: Calcinosis cutis following trauma. Pediatr Dermatol 22: 227, 2005.

  • 2.

    Le C, Bedocs PM: “Calcinosis Cutis,” in StatPearls [Internet], StatPearls Publishing, Treasure Island, FL, July 17, 2021.

  • 3.

    Reiter N, El-Shabrawi L, Leinweber B, et al: Calcinosis cutis: part II. Treatment options. J Am Acad Dermatol 65: 15, 2011.

  • 4.

    Sultan-Bichat N, Menard J, Perceau G, et al: Treatment of calcinosis cutis by extracorporeal shock-wave lithotripsy. J Am Acad Dermatol 66: 424, 2012.

  • 5.

    Nowaczyk J, Zawistowski M, Fiedor P: Local, non-systemic, and minimally invasive therapies for calcinosis cutis: a systematic review. Arch Dermatol Res 314: 515, 2022.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6.

    Sparsa A, Lesaux N, Kessler E, et al: Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shock wave lithotripsy. J Am Acad Dermatol 53(suppl 1): S263, 2005.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7.

    Joo YH, Kwon IH, Huh CH, et al: A case of persistent subepidermal calcified nodule in an adult treated with CO2 laser. J Dermatol 31: 480, 2004.

  • 8.

    Khudadah M, Jawad A, Pyne D: Calcinosis cutis universalis in a patient with systemic lupus erythematosus: a case report. Lupus 29: 1630, 2020.

  • 9.

    Lipskeir E, Weizenbluth M: Calcinosis circumscripta: indications for surgery. Bull Hosp Jt Dis Orthop Inst 49: 75, 1989.

  • 10.

    Johnson AR Jr, Mooshol D, Thakar V, et al: Surgical management of idiopathic ulcerative calcinosis cutis in the lower extremity: a case report. J Foot Ankle Surg 59: 603, 2020.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11.

    Wu JJ, Metz BJ: Calcinosis cutis of juvenile dermatomyositis treated with incision and drainage. Dermatol Surg 34: 575, 2008.

  • 12.

    Minami A, Suda K, Kaneda K, et al: Extensive subcutaneous calcification of the forearm in systemic lupus erythematosus. J Hand Surg Br 19: 638, 1994.

  • 13.

    Cousins MA, Jones DB, Whyte MP, et al: Surgical management of calcinosis cutis universalis in systemic lupus erythematosus. Arthritis Rheum 40: 570, 1997.

  • 14.

    Bernardo Cofiño J, Trapiella Martínez L: Superinfected calcinosis cutis as a presentation of a limited form systemic sclerosis. Rheumatol Clin 10: 187, 2014.

  • 15.

    Shahi V, Wetter DA, Howe BM, et al: Plain radiography is effective for the detection of calcinosis cutis occurring in association with autoimmune connective tissue disease. Br J Dermatol 170: 1073, 2014.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16.

    Limaiem F, Sergent SR: “Osteoma Cutis,” in StatPearls [Internet], StatPearls Publishing, Treasure Island, FL, July 22, 2021.

Leg Ulceration with Infected Calcinosis Cutis Mimicking Osteomyelitis: A Case Report

Fahad Hussain Foot and Ankle Surgery, RWJBarnabas Health–Community Medical Center, Toms River, NJ.

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Uzma Zafar Pathology, Cooperman Barnabas Medical Center, Livingston, NJ.

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Robin C. Lenz Ocean County Foot & Ankle Surgical Associates, Toms River, NJ.

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Calcified tissue exposed in a leg ulcer can become infected and develop into a nidus of infection leading to sepsis. This case details a patient with a leg wound secondary to skin biopsy. This leg ulceration did not heal due to an underlying calcified mass and led to five hospital admissions for sepsis. She was diagnosed as having calcinosis cutis, which was suspected to be the source of her infections. The calcified mass was resected, and she healed uneventfully without further infections. Calcified soft-tissue masses should be considered in nonhealing leg ulcers and ulcers with multiple recurrent infections. Radiographs can be used to diagnose this condition, and surgical excision can be considered in cases of infection.

Corresponding author: Fahad Hussain, DPM, Foot and Ankle Surgery, RWJBarnabas Health–Community Medical Center, 99 NJ-37, Toms River, NJ 08755. (E-mail: fahadhussaindpm@gmail.com)
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