Local antibiotic treatment of soft tissue and bone infections of the foot

DE Stabile Deaconess Hospital, St. Louis, MO.

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AM Jacobs Deaconess Hospital, St. Louis, MO.

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Twenty-seven pedal soft tissue and bone infections in 26 patients were treated with surgical necrectomy of infected tissues and implantation of antibiotic-loaded polymethyl methacrylate bone cement beads on chains. The definitive diagnosis of the infected tissues was obtained by culture and histologic examination in all of the cases. A wide variety of foot infections was successfully treated in this manner. The success rate without recurrence of osteomyelitis or soft tissue infection was 95% in this study at an average of 16 months after surgery.

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