Principles of wound healing and growth factor considerations

SJ SkokanPennsylvania College of Podiatric Medicine, Philadelphia.

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RH DavisPennsylvania College of Podiatric Medicine, Philadelphia.

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This review examines some of the important principles in wound repair and significant considerations for the use of growth factors. Moisture provides a positive influence on the mechanical and hormonal aspects of wounds. Atraumatic closure of surgical wounds and postoperative care and the types of wound closure are discussed. Cellular proliferation and migration in wounds are central features regarding growth factors.