Cover Journal of the American Podiatric Medical Association
Journal of the American Podiatric Medical Association
ISSN:
8750-7315
Online Publication Date:
Feb 1994

Anti-inflammatory and wound healing activity of a growth substance in Aloe vera

RH Davis Department of Biomedical Sciences, Pennsylvania College of Podiatric Medicine, Philadelphia.

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JJ Donato Department of Biomedical Sciences, Pennsylvania College of Podiatric Medicine, Philadelphia.

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GM Hartman Department of Biomedical Sciences, Pennsylvania College of Podiatric Medicine, Philadelphia.

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RC Haas Department of Biomedical Sciences, Pennsylvania College of Podiatric Medicine, Philadelphia.

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DOI:
https://doi.org/10.7547/87507315-84-2-77
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Aloe vera improves wound healing and inhibits inflammation. Since mannose-6-phosphate is the major sugar in the Aloe gel, the authors examined the possibility of its being an active growth substance. Mice receiving 300 mg/kg of mannose-6-phosphate had improved wound healing over saline controls. This dose also had anti-inflammatory activity. The function of mannose-6-phosphate in A. vera is discussed.

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