Possible therapeutic effects of growth hormone on wound healing in the diabetic patient

KA Massey Pennsylvania College of Podiatric Medicine, Philadelphia 19107, USA.

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C Blakeslee Pennsylvania College of Podiatric Medicine, Philadelphia 19107, USA.

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HS Pitkow Pennsylvania College of Podiatric Medicine, Philadelphia 19107, USA.

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Growth factors are increasingly investigated for their role in wound healing. The authors present evidence from human and animal studies suggesting that growth hormone induces a positive nitrogen balance, enhances connective-tissue synthesis, and increases lean body mass. The physiology of diabetes and wound healing is reviewed in the context of how growth hormone therapy could benefit this patient population.

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