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Patient Satisfaction with Oral versus Nonoral Therapeutic Approaches in Onychomycosis

David M. Stier Submitted as Vice President, The Lewin Group, San Francisco, CA.

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Douglas Gause Assistant Director, Health Economics and Outcomes Research, Novartis Pharmaceuticals Corp, East Hanover, NJ.

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Warren S. Joseph Submitted as Associate Professor of Medicine and Chief, Infectious Diseases, Pennsylvania College of Podiatric Medicine, Philadelphia, PA.

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Jeffrey R. Schein Submitted as Executive Director, Health Economics and Outcomes Research, Novartis Pharmaceuticals Corp, East Hanover, NJ. Mailing address:Janssen Pharmaceutica, Inc, 1125 Trenton-Harbourton Roads, Titusville, NJ 08580.

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Jeanette M. Broering Submitted as Project Director, The Lewin Group, San Francisco, CA.

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Karen L. Warolin Submitted as Database Manager/Analyst, The Lewin Group, San Francisco, CA.

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Joseph J. Doyle Submitted as Outcomes Research Manager, Novartis Pharmaceuticals Corp, East Hanover, NJ.

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The follow-up results of a 9-month observational study of 150 onychomycosis patients treated with a variety of mechanical, topical, and oral therapies by podiatric physicians and dermatologists are presented. Changes from baseline in toenail condition and patient satisfaction were assessed at 4- and 9-month follow-up. At 9 months, patients who had received oral therapy reported significantly fewer onychomycosis-related problems in social situations, including embarrassment or self-consciousness about the appearance of nails, avoidance of contact by others, being perceived as unclean or untidy, and the desire to keep their nails concealed. Patient-reported satisfaction with the treatment program was significantly higher for those receiving oral therapy than for those receiving nonoral therapy. (J Am Podiatr Med Assoc 91(10): 521-527, 2001)

This study was underwritten by Novartis Pharmaceuticals Corp, East Hanover, NJ.

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