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Wound Healing and Infection in Nail Matrix Phenolization Wounds

Does Topical Medication Make a Difference?

Russell Dovison BPod(Hons)1 and Anne-Maree Keenan BAppSc(Pod), MAppSc2
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  • 1 Director, Bayside Podiatry Pty Ltd, Bonbeach, Victoria, Australia.
  • | 2 Fellow, Australian Faculty of Public Health Medicine; Senior Lecturer, School of Exercise and Health Sciences, University of Western Sydney, Locked Bag 1797, Penrith DC, New South Wales 1797, Australia.
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After nail matrix ablation using phenolization, a medicated wound dressing (10% povidone iodine), an amorphous hydrogel dressing (Intrasite Gel), and a control dressing (paraffin gauze) were evaluated. Forty-two participants, randomly divided into three dressing groups, were evaluated. Healing time did not differ between the 10% povidone iodine (33 days), amorphous hydrogel (33 days), and the control dressing (34 days). For all groups, the clinical infection rate was lower than in previous studies, and there was no clinical difference between groups (one infection in the povidone iodine and control groups; none in the amorphous hydrogel group). However, in the amorphous hydrogel group, other complications, such as hypergranulation, were more likely. This investigation indicated that medicated or hydrogel dressings did not enhance the rate of healing or decrease infection rates. (J Am Podiatr Med Assoc 91(5): 230-233, 2001)