Cover Journal of the American Podiatric Medical Association
Journal of the American Podiatric Medical Association
ISSN:
8750-7315
  • 1

    Gupta R: A short history of neuropathic arthropathy. .Clin Orthop 296::43. ,1993. .

  • 2

    Sanders LJ, Frykberg RG: “Charcot Neuroarthropathy of the Foot,” in Levin and O’Neal’s The Diabetic Foot, 6th Ed, ed by JH Bowker, MA Pfeifer, p 439, CV Mosby, St Louis, 2001..

    • PubMed
    • Export Citation
  • 3

    Brower AC, Allman RM: The neuropathic joint: a neurovascular bone disorder. .Radiol Clin North Am 19::571. ,1981. .

  • 4

    Eloesser L: On the nature of neuropathic affections of the joints. .Ann Surg 66::201. ,1917. .

  • 5

    Johnson JT: Neuropathic fractures and joint injuries. .J Bone Joint Surg Am 49::1. ,1967. .

  • 6

    Brower AC, Allman RM: Pathogenesis of the neurotrophic joint: neurotraumatic versus neurovascular. .Radiology 139::349. ,1981. .

  • 7

    Frykberg RG, Mendeszoon E: Management of the diabetic Charcot foot. .Diabetes Metab Res Rev 16 (suppl 1)::S59. ,2000. .

  • 8

    Boulton AJ, Scarpello JH, Ward JD: Venous oxygenation in the diabetic neuropathic foot: evidence of arteriovenous shunting. ?Diabetologia 22::6. ,1982. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9

    Edmonds ME, Roberts VC, Watkins PJ: Blood flow in the diabetic neuropathic foot. .Diabetologia 22::9. ,1982. .

  • 10

    Edmonds ME, Clarke MB, Newton S, et al: Increased uptake of bone radiopharmaceutical in diabetic neuropathy. .QJM 57::843. ,1985. .

  • 11

    Gough A, Abraha H, Li F, et al: Measurement of markers of osteoclast and osteoblast activity in patients with acute and chronic diabetic Charcot neuroarthropathy. .Diabet Med 14::527. ,1997. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12

    Young MJ, Marshall A, Adams JE, et al: Osteopenia, neurological dysfunction, and the development of Charcot neuroarthropathy. .Diabetes Care 18::34. ,1995. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 13

    Cundy TF, Edmonds ME, Watkins PJ: Osteopenia and metatarsal fractures in diabetic neuropathy. .Diabet Med 2::461. ,1985. .

  • 14

    Eichenholtz SN: Charcot Joints, Charles C Thomas, Springfield, IL, 1966..

  • 15

    Shibata T, Tada K, Hashizume K, et al: The results of arthrodesis of the ankle for leprotic neuroarthropathy. .J Bone Joint Surg Am 72::749. ,1990. .

  • 16

    Schon LC, Marks RM: The management of neuropathic fracture-dislocations in the diabetic patient. .Orthop Clin North Am 26::375. ,1995. .

  • 17

    Sella EJ, Barrette C: Staging of Charcot neuroarthropathy along the medial column of the foot in the diabetic patient. .J Foot Ankle Surg 38::34. ,1999. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 18

    Grady JF, O’Connor KJ, Axe TM, et al: Use of electrostimulation in the treatment of diabetic neuroarthropathy. .JAPMA 90::287. ,2000. .

  • 19

    Hanft JR, Goggin JP, Landsman A, et al: The role of combined magnetic field bone growth stimulation as an adjunct in the treatment of neuroarthropathy/Charcot joint: an expanded pilot study. .J Foot Ankle Surg 37::510. ,1998. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 20

    Selby PL, Young MJ, Boulton AJ: Bisphosphonates: a new treatment for diabetic Charcot neuroarthropathy. ?Diabet Med 11::28. ,1994. .

  • 21

    Young MJ: The management of neurogenic arthropathy: a tale of two Charcots. .Diabetes Metab Res Rev 15::59. ,1999. .

  • 22

    Guis S, Pellissier JF, Arniaud D, et al: Healing of Charcot’s joint by pamidronate infusion. .J Rheumatol 26::1843. ,1999. .

  • 23

    Jude EB, Selby PL, Burgess J, et al: Bisphosphonates in the treatment of Charcot neuroarthropathy: a double-blind randomised controlled trial. .Diabetologia 44::2032. ,2001. .

    • PubMed
    • Search Google Scholar
    • Export Citation
Online Publication Date:
Apr 2002

Evaluation and Treatment of Stage 0 Charcot’s Neuroarthropathy of the Foot and Ankle

Gerard V. Yu Diplomate, American Board of Podiatric Surgery; Fellow, American College of Foot and Ankle Surgeons; Director of Podiatric Medical Education and Residency Training, St Vincent Charity Hospital, Cleveland, OH; Faculty Member, The Podiatry Institute, Tucker, GA. Mailing address: 23823 Lorain Rd, Ste 280, North Olmstead, OH 44070.

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Justin R. Hudson Submitted during third-year residency, St Vincent Charity Hospital, Cleveland, OH.

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DOI:
https://doi.org/10.7547/87507315-92-4-210
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Charcot’s neuroarthropathy is a relatively common disease in patients with diabetic neuropathy. If unrecognized or left untreated, Charcot’s neuroarthropathy can result in a severely misshapen and unstable foot and ankle. Ulceration, soft-tissue infection, and osteomyelitis frequently ensue, and partial or complete amputation of the foot is not uncommon. A high index of suspicion and proper interpretation of clinical and diagnostic findings are essential to establish a timely and accurate diagnosis and to institute appropriate treatment. The pathogenesis of neuroarthropathy is reviewed and diagnosis and treatment of the stage 0 diabetic Charcot foot are presented. (J Am Podiatr Med Assoc 92(4): 210-220, 2002)

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