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-
1
Scherer WP, Kinmon K: Dermatophyte test medium culture versus mycology laboratory analysis for suspected onychomycosis: a study of 100 cases in a geriatric population. .JAPMA 90::450. ,2000. .
-
2
Scherer WP, Scherer MD: Scanning electron microscope imaging of onychomycosis. .JAPMA 94::356. ,2004. .
-
3
Elewski BE: Diagnostic techniques for confirming onychomycosis. .J Am Acad Dermatol 35::S6. ,1996. .
-
4
McCarthy DJ: Origins of onychomycosis. .Clin Podiatr Med Surg 12::221. ,1995. .
-
5
Evans EGV: Causative pathogens in onychomycosis and the possibility of treatment resistance: a review. .J Am Acad Dermatol 38::S32. ,1998. .
-
6
Kemna ME, Elewski BE: A US epidemiologic survey of superficial fungal diseases. .J Am Acad Dermatol 35::539. ,1996. .
-
7
Schlefman BS: Onychomycosis: a compendium of facts and a clinical experience. .J Foot Ankle Surg 38::290. ,1999. .
-
8
Summerbell RC: Epidemiology and ecology of onychomycosis. .Dermatology 194::32. ,1997. .
-
9
Scherer WP, McCreary JP, Hayes WW: The diagnosis of onychomycosis in a geriatric population: a study of 450 cases in South Florida. .JAPMA 91::456. ,2001. .
-
10
Baran R, Dawber RP, Tosti A, et al: A Text Atlas of Nail Disorders, p 165, Martin Dunitz, London. ,1996. .
-
11
Rodgers P, Bassler M: Practical therapeutics. .Am Fam Physician 63::663. ,2001. .
-
12
Weinberg JM, Koestenblatt EK, Tutrone WD, et al: Comparison of diagnostic methods in the evaluation of onychomycosis. .J Am Acad Dermatol 49::193. ,2003. .
-
13
Funder S: Practical Mycology, 3rd Ed, p 79, Hafner Publishers, New York. ,1968. .
-
14
Daniel CR: The diagnosis of nail fungal infection. .Arch Dermatol 127::1566. ,1991. .
-
15
PDR Electronic Library, Thomson Micromedex, Greenwood Village, CO (edition expires 6/2004).
A Comparison of Results from Two Mycology Laboratories for the Diagnosis of Onychomycosis
A Study of 85 Cases in a Geriatric Population
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An investigative study was performed to compare the results from two mycology laboratories for the diagnosis of onychomycosis in a geriatric population and to determine the possible pharmacologic treatments based on the two laboratories’ results. In this study, 85 cases of suspected onychomycosis involving men and women 65 years and older from a nursing home setting in South Florida were used. Samples were taken from the hallux toenail and sent to two different mycology laboratories for fluorescent potassium hydroxide preparation and microscopic examination of a fungal culture. Of the 85 cases studied, the two mycology laboratories reported similar potassium hydroxide preparation results for 58.8% of the patients and similar fungal culture results for genus and species identification for 37.6% of the patients. When the potassium hydroxide preparation and fungal culture results were combined, the two mycology laboratories reported similar results for only 27.1% of the patients. As a result of the two mycology laboratories’ findings, the possible US Food and Drug Administration–approved pharmacologic treatments may differ for 43.5% of the patients studied. The discrepancy between the two independent laboratories leaves physicians to question the reproducibility of fluorescent potassium hydroxide preparation and fungal culture analysis in a geriatric patient population for the diagnosis of onychomycosis. (J Am Podiatr Med Assoc 94(6): 528–534, 2004)
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