Pigmented villonodular synovitis is nonmalignant and nonmetastasizing, but it is locally destructive and can result in considerable disability through infiltration and involvement of surrounding soft tissues and bone. This article briefly describes the clinical picture of the diffuse form of pigmented villonodular synovitis and reports on two cases involving juxta-articular erosions of the calcaneocuboid joint. Treatment involved substantial curettage of bone and resection of infiltrated intrinsic musculature. (J Am Podiatr Med Assoc 95(2): 161–166, 2005)
Corresponding author: Christopher P. Segler, DPM, Department of Podiatry, Veterans Affairs Medical Center, 500 Foothill Blvd, Ste 112, Salt Lake City, UT 84148.