• 1

    American Geriatric Society Panel on Exercise and Osteoarthritis: Exercise prescription for older adults with osteoarthritis pain: consensus practice recommendations. .J Am Geriatr Soc 49::808. ,2001. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 2

    Muehleman C, Bareither D, Huch K, et al: Prevalence of degenerative morphological changes in the joints of the lower extremity. .Osteoarthritis Cartilage 5::23. ,1997. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 3

    Kellgren JH, Lawrence JS: Atlas of Standard Radiographs: The Epidemiology of Chronic Rheumatism, Vol 2, Blackwell Scientific, Oxford. ,1963. .

    • PubMed
    • Export Citation
  • 4

    O’Grady M, Fletcher J, Ortiz S: Therapeutic and physical fitness exercise prescription for older adults with joint disease: an evidence-based approach. .Rheum Dis Clin North Am 26::617. ,2000. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5

    Altman RD, Fries JF, Bloch DA, et al: Radiographic assessment of progression in osteoarthritis. .Arthritis Rheum 30::1214. ,1987. .

  • 6

    Kelsey JL, Thompson WD, Evans AS: “Measurement Error,” in Methods in Observational Epidemiology, p 290, Oxford University Press, New York. ,1986. .

    • PubMed
    • Export Citation
  • 7

    Bull K, Spiegelhalter DJ: Tutorial in biostatistics: survival analysis in observational studies. .Stat Med 16::1041. ,1997. .

  • 8

    Dawson-Saunders B, Trapp RG: “Statistical Methods for Multiple Variables,” in Basic and Clinical Biostatistics, 2nd Ed, p 221, Appleton & Lange, Norwalk, CT. ,1994. .

    • PubMed
    • Export Citation
  • 9

    SAS Institute Inc: SAS Procedures Guide, Version 6, 3rd Ed, p 705, SAS Institute Inc, Cary, NC. ,1990. .

    • PubMed
    • Export Citation
  • 10

    Hulley SB, Cummings SR: Designing Clinical Research: An Epidemiologic Approach, p 216, Williams & Wilkins, Baltimore. ,1988. .

    • PubMed
    • Export Citation
  • 11

    McAlindon TE, Wilson PW, Aliabadi P, et al: Level of physical activity and the risk of radiographic and symptomatic knee osteoarthritis in the elderly: the Framingham study. .Am J Med 106::151. ,1999. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12

    Coggon D, Croft P, Kellinggray S, et al: Occupational physical activities and osteoarthritis of the knee. .Arthritis Rheum 43::1443. ,2000. .

  • 13

    Ettinger WH Jr, Burns R, Messier SP, et al: A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis: the Fitness Arthritis and Seniors Trial (FAST). .JAMA 277::25. ,1997. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14

    Rogers LQ, Macera CA, Hootman JM, et al: The association between joint stress from physical activity and self-reported osteoarthritis: an analysis of the Cooper Clinic data. .Osteoarthritis Cartilage 10::617. ,2002. .

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15

    Clyman B: Exercise in the treatment of osteoarthritis. .Curr Rheumatol Rep 3::520. ,2001. .

Effect of Regular Exercise on the Radiographic Progression of Foot Osteoarthritis

Frances V. Wilder The Arthritis Research Institute of America Inc, Clearwater, FL.

Search for other papers by Frances V. Wilder in
Current site
Google Scholar
PubMed
Close
 PhD
,
John P. Barrett Jr The Arthritis Research Institute of America Inc, Clearwater, FL.

Search for other papers by John P. Barrett Jr in
Current site
Google Scholar
PubMed
Close
 MD
, and
Edward J. Farina Sarasota Therapy Center, Sarasota, FL.

Search for other papers by Edward J. Farina in
Current site
Google Scholar
PubMed
Close
 PhD, MBA, PT

Among the elderly, osteoarthritis often causes chronic pain and disability. Although research has addressed the association between exercise and osteoarthritis, few studies have examined the effect of exercise on the radiographic progression of osteoarthritis. We investigated the relationship between ongoing exercise and radiographic progression of foot osteoarthritis. The first metatarsophalangeal and medial cuneiform–first tarsometatarsal joints were assessed. Joint-specific osteoarthritis radiographic progression scores were determined using four assessments: joint space narrowing, osteophytes, sclerosis, and a composite score. This cohort study included a subset of 221 men and women aged 40 to 91 years participating in a community-based osteoarthritis study. Adjusted risk estimates (95% confidence intervals) summarizing the relationship between ongoing exercise and radiographic progression in the first metatarsophalangeal joint ranged from 0.34 (0.11–0.99) for osteophytes to 0.66 (0.23–1.92) for sclerosis; because only eight individuals experienced medial cuneiform–first tarsometatarsal joint progression, these estimates were less stable, ranging from 2.41 (0.49–11.83) for composite to 4.29 (0.11–166.52) for osteophytes. Overall, our findings do not suggest that regular exercise is a risk factor for foot osteoarthritis progression. Future replication studies are warranted to confirm these findings. (J Am Podiatr Med Assoc 95(4): 342–346, 2005)

Corresponding author: Frances V. Wilder, PhD, Director of Research, The Arthritis Research Institute of America Inc, 300 S Duncan Ave, Ste 240, Clearwater, FL 33755.
Save