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Sesamoid tumors of the hallux are rare, and their incidence and differential diagnosis have not been well described. We present a case with a bizarre callus formation of the medial sesamoid of the hallux that mimicked a bone tumor. After excision of the mass and related sesamoid, the patient remained asymptomatic during 3 years of follow-up. (J Am Podiatr Med Assoc 95(6): 580–582, 2005)