Schissel D, Hivnor C, Elston D: Elephantiasis nostras verrucosa. .Cutis 62::77. ,1998. .
Sanders L, Slomsky J, Burger-Caplan C: Elephantiasis nostras: an eight year observation of progressive non-filarial elephantiasis of the lower extremity. .Cutis 42::406. ,1988. .
Rockson S: Lymphedema. .Am J Med 110::288. ,2001. .
Rowley M, Rapini R: Elephantiasis nostras. .Cutis 49::91. ,1992. .
Saccoman S, Rifleman G: Elephantiasis nostras verrucosa. .JAPMA 85::265. ,1995. .
Bargout R, Malhotra A: Lower leg edema and lichenification. .Postgrad Med 109::167. ,2001. .
Dean S: Images in vascular medicine: elephantiasis nostras verrucosa. .Vasc Med 5::261. ,2000. .
Castellani A: Researches on elephantiasis nostras and elephantiasis tropica with special regard to their initial stage of recurring lymphangitis (lymphangitis recurrens elephantogenica). .J Trop Med Surg 72::89. ,1969. .
Castellani A: Elephantiasis nostras (non-filarial elephantiasis). .J Trop Med Hyg 37::257. ,1934. .
Daroczy J: Antiseptic efficacy of local disinfecting povidone-iodine (Betadine) therapy in chronic wounds of lymphedematous patients. .Dermatology 204: (suppl 1):75. ,2002. .
Zouboulis C, Biczo S, Gollnick H, et al: Elephantiasis nostras verrucosa: beneficial effect of oral etretinate therapy. .Br J Dermatol 127::411. ,1992. .
Casley-Smith JR, Casley-Smith JR: The pathophysiology of lymphedema and the actions of benzo-pyrenes in reducing it. .Lymphology 21::190. ,1988. .
Tiwari A, Cheng K, Button M, et al: Differential diagnosis, investigation, and current treatment of lower limb lymphedema. .Arch Surg 138::152. ,2003. .
Swelling of the leg is a frequent finding in podiatric medicine. Unless the patient draws notice to the condition or the physician is diligent in asking questions and examining the extremity, the condition may be viewed as minor and given little attention. Swelling of the leg can be a clinical sign of certain systemic diseases, lymphatic and venous disorders, or other miscellaneous causes. Dermatologic consequences linked to many of these causes of swelling are well documented. What is not as well chronicled is a dramatic skin alteration associated with chronic lymphedema. This article provides an overview and a case presentation of the unusual and debilitating skin condition related to chronic lymphedema of the lower extremity known as elephantiasis nostras verrucosa. (J Am Podiatr Med Assoc 96(5): 442–444, 2006)