Conn RB: “Acute Leukemia,” in Current Diagnosis, 8th Ed, ed by R Conn, R Clohecy, H Conn, p 569, WB Saunders, Philadelphia. ,1991. .
Rogalsky RJ, Black GB, Reed MH: Orthopedic manifestations of leukemia in children. .J Bone Joint Surg Am 4::494. ,1986. .
Birrer RB, Dellacorte MP, Grisafi PJ: “The Arthropathies,” in Common Foot Problems in Primary Care, 2nd Ed, p 139, Hanley & Belfus, Philadelphia. ,1998. .
Yale I, Yale J: “Diagnostic and Therapeutic Considerations,” in The Arthritic Foot and Related Connective Tissue Disorders, p 117, Williams & Wilkins, Baltimore. ,1984. .
Wood ME, Bunn PA: “Acute Leukemia: Classification and Laboratory Evaluation,” in Hematology/Oncology Secrets, p 111, Hanley & Belfus, Philadelphia. ,1994. .
Saint S, Frances C: “Acute Leukemias,” in Saint-Frances Guide to Inpatient Medicine, p 369, Williams & Wilkins, Baltimore. ,1997. .
Zier BG: “Hematology and Oncology,” in Essentials of Internal Medicine in Clinical Podiatry, ed by BG Zier, p 313, WB Saunders, Philadelphia. ,1990. .
Ebb DH, Weinstein HJ: Diagnosis and treatment of childhood acute myelogenous leukemia. .Pediatr Clin North Am 44::847. ,1997. .
Jean-Baptiste G, De Ceulaer K: Osteoarticular disorders of haematological origin. .Baillieres Best Pract Res Clin Rheumatol 14::307. ,2000. .
Krey PR: “Arthropathies Associated with Hematologic Diseases,” in Primer on the Rheumatic Diseases, 10th Ed, ed by HR Schumacher, Jr, p 233, Arthritis Foundation, Atlanta. ,1993. .
Song KM, Sloboda JF: Acute hematogenous osteomyelitis in children. .J Am Acad Orthop Surg 9::166. ,2001. .
Faden H, Grossi M: Acute osteomyelitis in children: reassessment of etiologic agents and their clinical characteristics. .Am J Dis Child 145::65. ,1991. .
Nordon CW: Lessons learned from animal models of osteomyelitis. .Rev Infect Dis 10::103. ,1988. .
Lichtman MA: Acute Myelogenous Leukemia: Access Booklet, The Leukemia and Lymphoma Society, White Plains, NY. ,1999. .
Bernard EJ, Nichols WD, Howman-Giles RB, et al: Patterns of abnormality on bone scans in acute childhood leukemia. .J Nucl Med 39::1983. ,1998. .
Caudle RJ, Crawford AH, Gelfand MJ, et al: Childhood acute lymphoblastic leukemia presenting as “cold” lesions on bone scan: a report of two cases. .J Pediatr Orthop 7::93. ,1987. .
Miller JH, Ettinger LJ: Gallium citrate Ga 67 scintigraphic detection of chronic osteomyelitis in children with leukemia. .Am J Dis Child 140::230. ,1986. .
Levy LA: Foot and ankle ulcers associated with hematologic disorders. .Clin Podiatry 2::631. ,1985. .
McGlamry ED, Potter GK, Ward KA: “Tumors,” in Comprehensive Textbook of Foot Surgery, ed by ED McGlamry, AS Banks, MS Downey, Vol 2, p 1168, Williams & Wilkins, Baltimore. ,1992. .
Murphy RG, Greenberg ML: Osteomyelitis in pediatric patients with leukemia. .Cancer 62::2628. ,1988. .
Arceci RJ: Progress and controversies in the treatment of pediatric acute myelogenous leukemia. .Curr Opin Hematol 9::353. ,2002. .
Colby-Graham MF, Chordas C: The childhood leukemias. .J Pediatr Nurs 18::87. ,2003. .
The treating podiatric physician should consider underlying malignant disease when evaluating a child with any slowly healing or nonhealing infection involving the lower extremity. This article reports on an infant who was treated for suspected osteomyelitis involving his right fifth toe that did not improve with standard surgical, medical, and antibiotic treatments. He was later diagnosed as having acute myelogenous leukemia. (J Am Podiatr Med Assoc 97(2): 145–147, 2007)