Castellani A: Researches on elephantiasis nostras and elephantiasis tropica with special regard to their initial stage of recurring lymphangitis (lymphangitis recurrens elephantogenica). .J Trop Med Hyg 72::89. ,1969. .
Schissel DJ, Hivor C, Elston DM: Elephantiasis nostras verrucosa. .Cutis 62::77. ,1998. .
Schiff BL, Kern AB: Elephantiasis nostra. .Cutis 25::88. ,1980. .
Sanders LJ, Slomsky JM, Burger-Caplan C: Elephantiasis nostras: an eight-year observation of progressive non-filarial elephantiasis of the lower extremity. .Cutis 42::406. ,1988. .
Rowley MJ, Rapini RP: Elephantiasis nostras. .Cutis 49::91. ,1992. .
Baughman SA, Beninson J: Elephantiasis nostras: a case report. .Angiology 39::164. ,1988. .
Vaccaro M, Borgia F, Guarneri F, et al: Elephantiasis nostras verrucosa. .Int J Dermatol 39::764. ,2000. .
Bargout R, Malhotra A: Lower leg edema and lichenification. .Postgrad Med 109::167. ,2001. .
Harel L, Amir J, Nussinovitch M, et al: Lymphedema praecox seen as isolated unilateral arm involvement: case report and review of the literature. .J Pediatr 130::492. ,1997. .
Lewis JM, Wald ER: Lymphedema praecox. .J Pediatr 104::641. ,1984. .
Revis DR: Lymphedema. Available at: http://www.emedicine.com/med/topic2722.htm. Accessed August 2. ,2006. .
Bauer T, Wechselberger G, Schoeller T, et al: Lymphedema praecox of the lower extremity. .Surgery 132::899. ,2002. .
Usta M, Dilek K, Ersoy A, et al: A family with IgA nephropathy and hereditary lymphedema praecox. .J Intern Med 251::447. ,2002. .
Morton RA: Lymphedema praecox: a case report. .JAPMA 63::675. ,1973. .
Elephantiasis nostras verrucosa is a rare disorder that results from chronic obstructive lymphedema. It is characterized clinically by deforming, nonpitting edema; malodorous hyperkeratosis with generalized lichenification; cobblestoned papules; and verrucous changes, that often result in extreme enlargement of the involved body part. Although elephantiasis nostras verrucosa is striking in clinical appearance, biopsy reveals only moderately abnormal findings: pseudoepitheliomatous hyperplasia with dilated lymphatic spaces in the dermis, accompanied by chronic inflammation and fibroblast proliferation. The term elephantiasis nostras (nostras means “from our region”) has traditionally been used to differentiate temperate zone disease from the classic disease process, elephantiasis tropica, which is defined by chronic filarial lymphatic obstruction caused by Wuchereria bancrofti, Wuchereria malayi, or Wuchereria pacifica. We present a case report of elephantiasis nostras verrucosa arising as a result of lymphedema praecox. (J Am Podiatr Med Assoc 98(1): 66–69, 2008)