Laco JE: “Operative Care of Nail Disorders,” in Principles and Practice of Podiatric Medicine, ed by LA Levy, VJ Hetherington, p 499, Churchill Livingstone, New York. ,1990. .
Drago JJ, Jacobs AM, Oloff LA: A comparative study of postoperative care with phenol nail procedures. .J Foot Surg 22::332. ,1983. .
Greenwald L, Robbins HM: The chemical matricectomy: a commentary. .JAPA 71::388. ,1981. .
Moridani MY, Siraki A, O’Brien PJ: Quantitative structure toxicity relationships for phenols in isolated rat hepatocytes. .Chem Biol Interact 145::2133. ,2003. .
Unlu RE, Alagoz MS, Uysal AC, et al: Phenol intoxication in a child. .J Craniofac Surg 15::1010. ,2004. .
Lin TM, Lee SS, Lai CS, et al: Phenol burn. .Burns 32::517. ,2006. .
Horch R, Spilker G, Stark GB: Phenol burns and intoxications. .Burns 20::45. ,1994. .
Morkane AJ, Robertson RW, Inglis GS: Segmental phenolization of ingrowing toenail: a randomized controlled study. .Br J Surg 71::526. ,1984. .
Kimata Y, Uetake M, Tsukada S, et al: Follow-up study of patients treated for ingrown nails with the nail matrix phenolization method. .Plast Reconstr Surg 95::719. ,1995. .
Kordiak J, Santorek-Strumillo E, Brocki M, et al: The methods of treatment of an ingrown toenail. .Arch Med Sci 1::183. ,2005. .
Sugden P, Levy M, Rao GS: Onychocryptosis-phenol burn fiasco. .Burns 27::289. ,2001. .
Issa MM, Tanner WA: Approach to ingrowing toenails: the wedge resection/segmental phenolization combination treatment. .Br J Surg 75::181. ,1988. .
Tait GR, Tuck JS: Surgical or phenol ablation of the nail bed for ingrowing toenails: a randomised controlled trial. .J R Coll Surg Edinb 32::358. ,1987. .
Mogensen P: Ingrowing toenail: follow-up on 64 patients treated by labiomatricectomy. .Acta Orthop Scand 42::94. ,1971. .
Weisfeld M: Illustrated technique for the complete removal of nail matrix and hyponychium without skin incisions (Suppan nail technique no. 2). .JAPA 65::481. ,1975. .
Green DM, Klink B: Platelet gel as an intraoperatively procured platelet-based alternative to fibrin glue. .Plast Reconstr Surg 101::1161. ,1998. .
Valbonesi M, Giannini G, Migliori F: The role of autologous fibrin platelet glue in plastic surgery: a preliminary report. .Int J Artif Organs 25::334. ,2002. .
Mozena JD: The Mozena classification system and treatment algorithm for ingrown hallux nails. .JAPMA 92::131. ,2002. .
Pina-Barba MC, Tejeda-Cruz A, Regalado-Hernandez MA: Cerámicas mexicanas para cicatrización de piel. .Gac Med Mex 140::7. ,2004. .
Kuwada GT: “Cirugía de los Dedos Menores,” in Cirugía del antepié, 1st Ed, ed by R Butterworth, GL Dockery, p 137, Ortocen, Madrid, Spain. ,1992. .
Anitua E; Andia I, Sanchez M: PRGF (Plasma rico en factores de crecimiento). .Dental Dialogue 3::1. ,2004. .
Tayapongsak P, O’Brien DA, Monteiro CB, et al: Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow. .J Oral Maxillofac Surg 52::161. ,1994. .
Gerritsma-Blecker C, Klaase J, Geelkerken R, et al: Partial matrix excision or segmental phenolization for ingrowing toenails. .Arch Surg 13::320. ,2002. .
Farley-Sakevich T, Grady JF, Zager E, et al: Onychoplasty with carbon dioxide laser matrixectomy for treatment of ingrown toenails. .JAPMA 95::175. ,2005. .
Lorente A, Rodriguez F: ¿Conseguimos plasma concentrado rico en plaquetas de forma ambulatoria?. Cient Dent 2::73. ,2005. .
Zimmermann R, Jakubietz R, Jakubietz M, et al: Different preparation methods to obtain platelet components as a source of growth factors for local application. .Transfusion 41::1217. ,2001. .
Weibrich G, Kleis WK, Hafner G: Growth factor levels in the platelet-rich plasma produced by 2 different methods: curasan-type PRP kit versus PCCS PRP System. .Int J Oral Maxillofac Implants 17::184. ,2002. .
Marx R: Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation. .J Oral Maxillofac Surg 58::300. ,2000. .
Barnett MD, Pomeroy GC: Use of platelet-rich plasma and bone marrow-derived mesenchymal stem calls in foot and ankle surgery. .Techniques Foot and Ankle Surg 6::89. ,2007. .
Background: The growth factors derived from platelets contained in platelet-rich plasma comprise a series of molecules that favor the production of collagen with the proliferation of fibroblasts and new blood vessels. These substances exert their effect on the cells, acting in all the stages of cicatrization, especially in hemostasis and early fibroplasia.
Methods: Thirty-five patients (70 feet) were selected, operated on both sides for ingrown hallux nails, and subjected to two different experimental conditions in a crossover clinical trial with positive control of treatment. Two main variables were analyzed: on one side, the bleeding, according to three preestablished categories, and on the other, the mean time of cicatrization in days.
Results: Significant differences (P < .001) were found between the two groups for bleeding. We observed that cicatrization time did not differ significantly between the two treatments.
Conclusion: The use of platelet gel for the treatment of onychocryptosis by single nonincisional matricectomy can guarantee good hemostasis, with a significant reduction in bleeding, but does not produce a clinically significant reduction in cicatrization time. (J Am Podiatr Med Assoc 98(4): 296–301, 2008)