Early Clinical Experience with the Use of a New Allograft Adipose Matrix for Foot Fat Pad Restoration

Jodi Schoenhaus GoldFoot, Ankle & Leg Vein Surgery, JRSG Consulting, LLC, 670 Glades Road, Ste 320, Boca Raton, FL.

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Background: Fat pad atrophy is the loss of subcutaneous tissue in the plantar foot, inhibiting the cushioning function. Patients experience severe pain upon ambulation from high-pressure forces. Soft tissue augmentation or fat pad restoration is performed to improve the thickness and cushioning ability of the subcutaneous layer. A first-of-its-kind, allograft adipose matrix (AAM), which has been reported to support native fat pad restoration, was evaluated to address fat pad atrophy and the cushioning ability in the plantar foot.

Method: An IRB approved retrospective study review and analysis on 16 patients (21 feet) treated with AAM in the plantar foot was conducted. Adverse events and a patient subjective evaluation of percentage improvement were reported, sometimes supported by imaging.

Results: The average volume of AAM injected was 2.2±0.7cc (1.5-2.6cc range) with a follow-up time of 3-20 months, in patients aged 68.6±8.9 years. Overall minimal adverse events were observed and the percentage improvement, as per patient feedback, was 72.9±23.0% (100% corresponds to fully satisfied). The quality of skin improved with reduced presence of callus and patients resumed their daily activities.

Conclusion: AAM can support endogenous fat pad restoration by supplementing fat thickness and its natural cushioning ability. The early clinical observations in this retrospective study review demonstrated that patients could resume daily activities after treatment.